Protein Alignment Jhedup and cest-33

DIOPT Version :9

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_504621.1
• Gene: cest-33 / 179020
• WormBaseID: WBGene00017431
• Length: 554
• Species: Caenorhabditis elegans
• Alignment Length: 584
• Identity: 168/584 - (28%)
• Similarity: 260/584 - (44%)
• Gaps: 133/584 - (22%)

  Fly    28 GCMRGTLMPGYQSGE--FEAFMGIPFAQPPVGPLRLKNPVPNEPWEGVLDAGAAKDSCIQRSYF- 89
            |.:||.:   |:..:  .:.::|||:|:||||.||.|.||..:.|..:.|......:|:|...|
 Worm    22 GPVRGNI---YKHDDVIVDGYLGIPYAKPPVGELRFKKPVTVDVWTEIKDCYKYGPACVQTGGFE 83

  Fly    90 ---------AKEWGLMGVEDCLYLNVYRPKNRA---EDKLPVMVYIHGGGF-FSGSAHPMASGPE 141
                     .:|.|      ||.|||:.|:|.:   ::..||||||||||: ...|:...|....
 Worm    84 QIAGPRTPTPEEAG------CLTLNVFTPRNASSEFKNGRPVMVYIHGGGYELCASSDFCAYSLS 142

  Fly   142 YLMDTNKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQRLALQWIQKHIATFGGDPKKVTVLGH 206
            ..:....||:|::|||||.||||:|||...|||||..||.|||:|:||||::|||||..|||.|.
 Worm   143 GTLPLKDVVVVSINYRLGVFGFLTTGDNVCPGNFGLWDQTLALKWVQKHISSFGGDPNCVTVFGQ 207

  Fly   207 SAGGISAHLHMISPNSKGLFQNSMSLTGTMFLSAMKILKDPLSQARRLGKELAIDQAESLSSQDL 271
            ||||.|..|..:||:|:.|||..:.::||.....  .::...:|| ::.:|.|  :....|.:|.
 Worm   208 SAGGASTDLLSLSPHSRDLFQRFIPISGTAHCDF--AIRASENQA-KIFREFA--EFHGFSGRDS 267

  Fly   272 A-----------EALRNVCPKKLLVSVDSLKVWDNMPHLTTLPVLEAPSPDAFLVEDPLDAHR-- 323
            :           |.|.||...|..:|          ..||.:|.|:.   |.|  ..|||..|
 Worm   268 SALFKWYQEQSPETLSNVKGYKKSIS----------GFLTFIPNLDG---DFF--PKPLDELRKE 317

  Fly   324 AGRINQMPWILSLSSRAGEGSLFIMRAFINPKLRAEFNENFLEHMALLLNLPEG--------TPV 380
            |.:...|..:...     ||   :|.|.:||....       ..:.|.| :|:|        .|.
 Worm   318 APKKQMMTGVTEY-----EG---LMLASMNPAFSP-------ADVGLTL-MPQGIYGKDVVSNPD 366

  Fly   381 QMVSEILDAYDFKGDSLNNDTML--KLAEISGDFNFYYPIYETISSYVTYANLEENPLFIYIFEF 443
            ::.....:.| .:|...:::..:  ||.|..||..|...:.:...:...:.    |.::.|.||:
 Worm   367 EIQKIFYEKY-VEGVDKSDELAMRKKLCEALGDEFFNVGVIQAAKNAAKHG----NEVYFYTFEY 426

  Fly   444 AGLNSITKFFAGTTDDYGL--------GAVHMDDGLHTIRIPVSFDDFPKDSEDAKVIQRMSSLM 500
            .           ..|.:|:        .|||..:..:.:...| :..|....||.||::..::|.
 Worm   427 V-----------NPDSFGMWDGMMPFKAAVHCTELRYLLGEGV-YSKFEPTEEDRKVMETTTTLF 479

  Fly   501 TDFAKTG----------VFHEESI-------------CKVSDFKEQGMCNYLH-FGGNKEKYLE 540
            ::|||.|          ::.:.|:             |::.|...:|...:|. ..|:.:||.|
 Worm   480 SNFAKYGNPNGKGATAEIWEKYSLNRPERHYRISYPKCEMRDVYHEGRIQFLEKIDGDSDKYQE 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	COesterase	31..508	CDD:278561	158/533 (30%)
		Aes	<106..>210	CDD:223730	56/107 (52%)
cest-33	NP_504621.1	Esterase_lipase	16..521	CDD:238191	161/560 (29%)
		Aes	<103..>224	CDD:223730	62/120 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810