Protein Alignment Jhedup and cest-35.2

DIOPT Version :10

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_504398.1
• Gene: cest-35.2 / 178910
• WormBaseID: WBGene00016863
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 537
• Identity: 156/537 - (29%)
• Similarity: 223/537 - (41%)
• Gaps: 134/537 - (24%)

  Fly    28 GCMRGTLMPGYQSGE--FEAFMGIPFAQPPVGPLRLKNPVPNEPWEGVLDAGAAKDSCIQRSYFA 90
            |.:||.:   |:.|:  ...::|||||:.|:|.||.|..|..|.|...||.......|.|.:...
 Worm    22 GPIRGNV---YEHGDKIVNGYLGIPFAKAPIGDLRFKKSVEAEKWTQPLDCYKYGPGCPQSAALG 83

  Fly    91 KEWGLM---------GVEDCLYLNVYRPKNRAED---KLPVMVYIHGGGFFSGSAHPM----ASG 139
               .||         ..::||.|||:.||.::.:   ..|||||.:||||..|.:...    .:|
 Worm    84 ---ALMVSQATNHDFAEDNCLNLNVFAPKWKSAEFPNGFPVMVYFYGGGFEVGFSSMFDDYSLTG 145

  Fly   140 PEYLMDTNKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQRLALQWIQKHIATFGGDPKKVTVL 204
            ...|.|   |::||.|||:||.||.:|||:...||:|..||.|||||:||||.:|||||..||:.
 Worm   146 TLPLKD---VILVTPNYRIGPLGFFATGDDVARGNWGLWDQALALQWVQKHIKSFGGDPSNVTIS 207

  Fly   205 GHSAGGISAHLHMISPNSKGLFQNSMSLTGTM---FLSAMK-----ILKDPLSQARRLGKELAID 261
            |.||||.|.....:||::...||..:.::|..   |....|     |.::..:.....|.:
 Worm   208 GTSAGGASVDFLSLSPHANKYFQKFIPMSGAATCPFGIRSKDVEGLIFREFANHHGYTGND---- 268

  Fly   262 QAESL----SSQD-----LAEALRNVCPKKLLVSVDSLKVWDNMPHLTTLPVLEAPSPDAFLVED 317
             ::||    .|||     .||..:  ||...:.|.                   .|:.|......
 Worm   269 -SKSLLQWYQSQDSEIFLKAEGYK--CPASGMFSF-------------------VPNFDGDFFPK 311

  Fly   318 PLDAHRAGRINQMPWILSLSSRAGEGSLFIMRAFINPKLRAEFNENFLEHMALLLNLPEGTPVQM 382
            |.|..|. ...::..|:|:....|.|.                 |:|.        ..:.||.||
 Worm   312 PFDELRK-EAPKLGAIVSIGEYEGLGF-----------------EDFY--------AGQKTPQQM 350

  Fly   383 VSEIL----------------DAYDFKGDSLNNDTMLK-LAEISGDFNFYYPIYETISSYVTYAN 430
            :|..|                ::|...|.:.|.:.:.| |.||.||:.|....::|:.|.|.|.|
 Worm   351 LSAALGPEVVRNREEVVKRAAESYLKNGGNENEENIAKTLVEIFGDYYFSVGAFDTVRSLVKYGN 415

  Fly   431 LEENPLFIYIFEFAGLNSITKFFAGTTDDYGLGAVHMDD-----GLHTIRIPVSFDDFPKDSEDA 490
            .      :|::.|...|..|....|....:. .|.|..|     |..|       .:|.|  ||.
 Worm   416 T------VYLYSFNYFNPNTPIVFGKNRPFN-AANHGSDLRYIFGEGT-------GEFSK--EDR 464

  Fly   491 KVIQRMSSLMTDFAKTG 507
            :|:..|.:..|:|||.|
 Worm   465 QVMDMMGTYHTNFAKYG 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	alpha/beta hydrolases	31..508	CDD:473884	155/534 (29%)
cest-35.2	NP_504398.1	COesterase	18..517	CDD:395084	156/537 (29%)