Protein Alignment Jhedup and cest-35.2

DIOPT Version :9

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_504398.1
• Gene: cest-35.2 / 178910
• WormBaseID: WBGene00016863
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 537
• Identity: 156/537 - (29%)
• Similarity: 223/537 - (41%)
• Gaps: 134/537 - (24%)

  Fly    28 GCMRGTLMPGYQSGE--FEAFMGIPFAQPPVGPLRLKNPVPNEPWEGVLDAGAAKDSCIQRSYFA 90
            |.:||.:   |:.|:  ...::|||||:.|:|.||.|..|..|.|...||.......|.|.:...
 Worm    22 GPIRGNV---YEHGDKIVNGYLGIPFAKAPIGDLRFKKSVEAEKWTQPLDCYKYGPGCPQSAALG 83

  Fly    91 KEWGLM---------GVEDCLYLNVYRPKNRAED---KLPVMVYIHGGGFFSGSAHPM----ASG 139
               .||         ..::||.|||:.||.::.:   ..|||||.:||||..|.:...    .:|
 Worm    84 ---ALMVSQATNHDFAEDNCLNLNVFAPKWKSAEFPNGFPVMVYFYGGGFEVGFSSMFDDYSLTG 145

  Fly   140 PEYLMDTNKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQRLALQWIQKHIATFGGDPKKVTVL 204
            ...|.|   |::||.|||:||.||.:|||:...||:|..||.|||||:||||.:|||||..||:.
 Worm   146 TLPLKD---VILVTPNYRIGPLGFFATGDDVARGNWGLWDQALALQWVQKHIKSFGGDPSNVTIS 207

  Fly   205 GHSAGGISAHLHMISPNSKGLFQNSMSLTGTM---FLSAMK-----ILKDPLSQARRLGKELAID 261
            |.||||.|.....:||::...||..:.::|..   |....|     |.::..:.....|.:
 Worm   208 GTSAGGASVDFLSLSPHANKYFQKFIPMSGAATCPFGIRSKDVEGLIFREFANHHGYTGND---- 268

  Fly   262 QAESL----SSQD-----LAEALRNVCPKKLLVSVDSLKVWDNMPHLTTLPVLEAPSPDAFLVED 317
             ::||    .|||     .||..:  ||...:.|.                   .|:.|......
 Worm   269 -SKSLLQWYQSQDSEIFLKAEGYK--CPASGMFSF-------------------VPNFDGDFFPK 311

  Fly   318 PLDAHRAGRINQMPWILSLSSRAGEGSLFIMRAFINPKLRAEFNENFLEHMALLLNLPEGTPVQM 382
            |.|..|. ...::..|:|:....|.|.                 |:|.        ..:.||.||
 Worm   312 PFDELRK-EAPKLGAIVSIGEYEGLGF-----------------EDFY--------AGQKTPQQM 350

  Fly   383 VSEIL----------------DAYDFKGDSLNNDTMLK-LAEISGDFNFYYPIYETISSYVTYAN 430
            :|..|                ::|...|.:.|.:.:.| |.||.||:.|....::|:.|.|.|.|
 Worm   351 LSAALGPEVVRNREEVVKRAAESYLKNGGNENEENIAKTLVEIFGDYYFSVGAFDTVRSLVKYGN 415

  Fly   431 LEENPLFIYIFEFAGLNSITKFFAGTTDDYGLGAVHMDD-----GLHTIRIPVSFDDFPKDSEDA 490
            .      :|::.|...|..|....|....:. .|.|..|     |..|       .:|.|  ||.
 Worm   416 T------VYLYSFNYFNPNTPIVFGKNRPFN-AANHGSDLRYIFGEGT-------GEFSK--EDR 464

  Fly   491 KVIQRMSSLMTDFAKTG 507
            :|:..|.:..|:|||.|
 Worm   465 QVMDMMGTYHTNFAKYG 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	COesterase	31..508	CDD:278561	155/534 (29%)
		Aes	<106..>210	CDD:223730	53/110 (48%)
cest-35.2	NP_504398.1	COesterase	14..515	CDD:278561	156/537 (29%)
		Aes	<105..>239	CDD:223730	61/136 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157219
Domainoid	1	1.000	183	1.000	Domainoid score	I2040
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	183	1.000	Inparanoid score	I2624
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.800