Protein Alignment Jhedup and cest-32

DIOPT Version :9

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_504397.1
• Gene: cest-32 / 178909
• WormBaseID: WBGene00016862
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 597
• Identity: 161/597 - (26%)
• Similarity: 249/597 - (41%)
• Gaps: 147/597 - (24%)

  Fly    19 SLDVCLEDMGCMRGTLMPGYQSGE--FEAFMGIPFAQPPVGPLRLKNPVPNEPWEGVLDAGAAKD 81
            ||:|.....|.:.|.:   |:..:  ...::|||||:.|:..||.|.||..|.|...|:......
 Worm    13 SLEVLNASCGPVIGNI---YRHDDKIVNGYLGIPFAKAPICELRFKKPVEAEKWTKPLNCHKYGP 74

  Fly    82 SCIQRSY------------FAKEWGLMGVEDCLYLNVYRPKNRAED---KLPVMVYIHGGGFFSG 131
            .|.|..:            ||:       ::||.||::.|..::|:   .||:|||.|||||..|
 Worm    75 GCPQSGHMISNLLPPGYREFAE-------DNCLNLNIFAPSWKSEEFPNGLPIMVYFHGGGFEIG 132

  Fly   132 SAHPM----ASGPEYLMDTNKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQRLALQWIQKHIA 192
            .:...    .||...|.|   |::||.|||:||.||::||||...||:|..||.|||:|:|:||.
 Worm   133 FSSMFDDYSLSGTLPLKD---VIVVTANYRVGPLGFMTTGDEVSRGNYGLWDQTLALKWVQEHIK 194

  Fly   193 TFGGDPKKVTVLGHSAGGISAHLHMISPNSKGLFQNSMSLTGTMFLSAMKILKDPLSQ-----AR 252
            :|||:|..|||.|.||||:||.|..:||:|..||...|:::|:.|.......|:..::     |:
 Worm   195 SFGGNPNIVTVCGTSAGGVSAGLLALSPHSNKLFHRFMAMSGSAFCEFSIRTKEQEAEIFRNFAK 259

  Fly   253 RLGKELAIDQAESL----SSQDLAEALRNVCPKK----LLVSVDSL------KVWDNMPHLTTLP 303
            ..|.|  .:.:|||    .||.|::.......:|    .|..:.:.      |.:|.:..
 Worm   260 HHGYE--GEDSESLLEWYKSQPLSKFQETATFEKKASGFLTFIPNFDGDFFPKPFDELSR----- 317

  Fly   304 VLEAPSPDAFLVEDPLDAHRAGRINQMPWILSLSSRAGEGSLFIMRAFINPKLRAEFNENFLEHM 368
              |||..||....|..:.        :.::....||..:..:          :::.|..:.:|:
 Worm   318 --EAPKLDAMATVDEYEG--------LGFLTMFQSRRNDMDI----------IKSSFGSDVVEN- 361

  Fly   369 ALLLNLPEGTPVQMVSEILDAYDFKGDSLNNDTML--KLAEISGDFNFYYPIYETISSYVTYA-- 429
                      .|.:...|::.| .|....|:|..:  :|.::..|..|.....||:.:...|.
 Worm   362 ----------AVDVQKRIMEFY-MKNIDKNDDKAVEKRLIQLISDSWFNIGALETVKTSTKYGSN 415

  Fly   430 ---------NLEENPLFIYIFEFAGLN--SITKFFAGTTDDYGLGAVHMDDGLHTIRIPVSFDDF 483
                     |:..|..:...|.|...|  |..|:..|.    |:|                  .|
 Worm   416 AYLGSFDYYNMGSNDPYATWFPFKAANHGSELKYMLGE----GMG------------------KF 458

  Fly   484 PKDSEDAKVIQRMSSLMTDFAK----TGVFHEE-----------SICKVSDFKEQGMCNYLHFGG 533
            ....|:.|||..|.:|..:|.|    .|:...|           |..|: |:.:..|.:  :|..
 Worm   459 SPIEEEFKVIDMMGTLTANFVKYGNPNGINGPELWKKYTPEKPYSYFKI-DYPKSEMRD--NFQD 520

  Fly   534 NKEKYLEDIRNS 545
            .:.|..|||..|
 Worm   521 GRLKLFEDINKS 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	COesterase	31..508	CDD:278561	145/535 (27%)
		Aes	<106..>210	CDD:223730	53/110 (48%)
cest-32	NP_504397.1	COesterase	15..516	CDD:278561	153/575 (27%)
		Aes	<104..>227	CDD:223730	61/125 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157217
Domainoid	1	1.000	183	1.000	Domainoid score	I2040
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	183	1.000	Inparanoid score	I2624
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.790