Protein Alignment Jhedup and cest-10

DIOPT Version :10

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_501133.3
• Gene: cest-10 / 177493
• WormBaseID: WBGene00016595
• Length: 579
• Species: Caenorhabditis elegans
• Alignment Length: 538
• Identity: 126/538 - (23%)
• Similarity: 205/538 - (38%)
• Gaps: 119/538 - (22%)

  Fly     2 LFAGFGVLLFVAVAVGDSLDVCLEDMGCMRGTL--MPGYQSGEFEAFMGIPFAQPPVGPLRLKNP 64
            |..|..:|...:.:       |..|...:..:|  :.|.|.|.|..|..||||:||:|.||.:.|
 Worm     3 LLPGIQILFLFSFS-------CFVDSVIVETSLGKLNGDQIGNFHLFKKIPFAKPPLGKLRFQKP 60

  Fly    65 VPNEPWEGVLDAGAAKDSCIQRSYFAKEWGLMGVEDCLYLNVYRPKNRAEDK-LPVMVYIHGGGF 128
            .|.|.|.||.:|.....:|:..|...|.......||||:||::..:...:.| ..|::|:|||..
 Worm    61 QPAETWNGVRNAKDYGPACMSNSSTTKTVQKWVDEDCLHLNIFTSETCLKSKNCAVVIYLHGGNL 125

  Fly   129 FSGSAHPMASGPEYLMDT---NKVVMVTMNYRLGPFGFLSTGDEHM-PGNFGFKDQRLALQWIQK 189
            ...||  :.....:|:.|   .::|.|....|||.|......|:.: |.|....|...|:::.:.
 Worm   126 HYDSA--VMFNDTFLLHTYASQEIVFVIPAVRLGIFSHFVVEDQSIAPNNLALFDMLQAMEFAKS 188

  Fly   190 HIATFGGDPKKVTVLGHSAGGISAHLHMISPNSK-----GLFQNSMSLTGTMFLSAMKILKDPLS 249
            .|..|||:.|:.|:||||.||..|  .|:|.::|     .|||..:|::.......:::   .:.
 Worm   189 DIHNFGGNNKRTTLLGHSYGGTVA--SMLSFSTKVNTDLSLFQQYISMSSPTNFDTLEL---QVE 248

  Fly   250 QARRLGKEL-AIDQAESLSSQDLAEALRNVCPKKLLVSVDSLKVWDNMPHLTTLP-----VLEAP 308
            :..|..:.. .:.:......::..|.....|.||...| :.|::..::.. ...|     |:..|
 Worm   249 RTYRFAEHANCLPKNSKFMRKNQKEVYMRDCLKKKSAS-ELLRIQRSLEE-AGYPVYGGSVMRGP 311

  Fly   309 SPDAFLVEDPLDAHRAGRINQMPWILSLSS-------RAGEGSLFIMRAFINPKLRAEFNENFLE 366
            .....|..|.:|:  ...|..:.......|       ..|:...|.....:|.|.|::..|..:|
 Worm   312 IFQEVLERDFMDS--PNNITSLTGCTKYESLVYDHYRNMGKALGFENYEEVNEKYRSDSKEGKIE 374

  Fly   367 HMALLLNLPEGTPVQMVSEILDAYDFKGDSLNNDTMLKLAEISGDFNFYYPIYETISSYVTYAN- 430
            .                           |::.|.|.:.|.:|.                 |..|
 Worm   375 F---------------------------DNVKNATQIMLIQIR-----------------TRVNK 395

  Fly   431 -LEENPLFIYIFEFAGLNSITKFFAGTTDDYGLGAVHMDD-----GLHTIRIPVSFDDFPKDSED 489
             |::| :..|.:|:|               |...|.|.||     |:|         .|.:|..:
 Worm   396 ILKKN-IPAYHYEYA---------------YPKHANHTDDLFFIMGVH---------PFIQDENE 435

  Fly   490 AKVIQRMSSLMTDFAKTG 507
            .|:.....|:..:|.|||
 Worm   436 IKLGNFYRSMFLNFIKTG 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	alpha/beta hydrolases	31..508	CDD:473884	121/509 (24%)
cest-10	NP_501133.3	alpha/beta hydrolases	20..503	CDD:473884	122/514 (24%)