Protein Alignment Jhedup and cest-6

DIOPT Version :9

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_501070.1
• Gene: cest-6 / 177459
• WormBaseID: WBGene00020688
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 571
• Identity: 131/571 - (22%)
• Similarity: 216/571 - (37%)
• Gaps: 161/571 - (28%)

  Fly     6 FGVLLFVAVAVGDSLDVCLEDMGCMRGTL--MPGYQSGEFEAFMGIPFAQPPVGPLRLKNPVPNE 68
            |.:|:||.:.|..:...|  :.|.:..:|  :.|.|.|.::.|..||||:||:|.||.:.|:..|
 Worm     4 FDMLIFVLLIVYSAYKSC--EAGVITTSLGSINGNQIGSYQTFKKIPFAKPPIGKLRFQKPMAAE 66

  Fly    69 PWEGVLDAGAAKDSCIQRSYFAKEWGLMGVEDCLYLNVYRPKNRAEDK-LPVMVYIHGGGFFSGS 132
            .|||:|:|.....:|:..|..:|.......||||::|::........| ..|:.|:|||.....|
 Worm    67 KWEGILNATEYGPACMSNSSTSKSPQKWIDEDCLHINIFTTDTCLSSKNCSVVFYVHGGELVYDS 131

  Fly   133 AHPMASGPEYLMDT---NKVVMVTMNYRLGPFGFLSTGDEHM-PGNFGFKDQRLALQWIQKHIAT 193
            |  :....:||.||   ..|::|...:|||.|......|::: |.|....|..|||::::..|..
 Worm   132 A--VMFEDKYLFDTFSSRDVILVIPAFRLGLFSHFVVEDQNVAPNNLALYDILLALEFVKSEIHN 194

  Fly   194 FGGDPKKVTVLGHSAGGISAHLHMISPNSKGLFQNSMSLTGTMFLSAMKILKDPLSQARRLGKEL 258
            |||...:||..|||.||     |::|               .|..|.                |:
 Worm   195 FGGSSDRVTAFGHSYGG-----HVVS---------------VMAFST----------------EI 223

  Fly   259 AIDQAESLSSQDLAEALRNVCPKKLLVSVDSLKVWDNM-----------------------PHLT 300
                     :.||:...|.:|       :.|:.|||::                       ..:|
 Worm   224 ---------NTDLSYFQRVIC-------MSSVNVWDSLEFEIEKTMRFIQYANCSVPQDLKSRMT 272

  Fly   301 TLPVLEAPSPDAFLVEDPLDAHRAGRINQMPWILSLSSRAGEG----SLFIMRAFINPKLRAEFN 361
            :.      ..|::::|...|      |:.|..:....|...||    |..::|   .|.::....
 Worm   273 SF------EQDSYMMECLQD------IDSMELLRIQRSLEDEGHPIYSGLVLR---EPLIQNVLV 322

  Fly   362 ENFLEHMALLLNLPEGTPVQMVSEILDAYDFKGDSLNNDTMLKLAEISGDFNFYYPIYETISSYV 426
            ::|.|.       |:..|                :|...|..:|.:    |:.|:.|.||: .|.
 Worm   323 QDFYEK-------PKNIP----------------TLTGCTYKELDK----FHAYHNIVETL-GYE 359

  Fly   427 TYANLEEN----------PLFIYIFEFAGLNSITKFFAGTTDDYGLGAVHMDDGLHTIRIPVSFD 481
            .|...::.          .|..:..|..|:.:.||.....         .:|.|:.|.....|:.
 Worm   360 NYKECDDKYRDDRKYGRFDLNKHADETFGILAQTKLKVDK---------QLDKGIPTYFYEYSYP 415

  Fly   482 DFPKDSEDAKVIQRMSSLMTDFAKTGVFHEESICKVSDFKEQGMCNYLHFG 532
            ..|..::|...|..:.:...|        |..|.....::|..| |::.||
 Worm   416 KHPSHTDDLSYIMGVHAFEKD--------ENEIHLAKSYQEMFM-NFVKFG 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	COesterase	31..508	CDD:278561	117/520 (23%)
		Aes	<106..>210	CDD:223730	34/108 (31%)
cest-6	NP_501070.1	Abhydrolase	25..500	CDD:389770	124/548 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156882
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740