Protein Alignment Jhedup and cest-4

DIOPT Version :9

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_501043.1
• Gene: cest-4 / 177445
• WormBaseID: WBGene00015930
• Length: 592
• Species: Caenorhabditis elegans
• Alignment Length: 552
• Identity: 127/552 - (23%)
• Similarity: 216/552 - (39%)
• Gaps: 148/552 - (26%)

  Fly     1 MLFAGFGVLLF-------VAVAVGDSLDVCLEDMGCMRGTLMPGYQSGEFEAFMGIPFAQPPVGP 58
            :||..| .|||       |:.::|.                :.|.|.|.|..|..||.|:||:|.
 Worm    12 LLFLSF-FLLFSITKSAIVSTSLGQ----------------IDGDQIGSFHLFKHIPLAKPPIGK 59

  Fly    59 LRLKNPVPNEPWEGVLDAGAAKDSCIQRSYFA---KEWGLMGVEDCLYLNVYRPKNRAEDK-LPV 119
            ||.:.|.|.|.|.||.:|.|...:||..|..:   ::|   ..||||::|::......:.| ..|
 Worm    60 LRFQKPEPPEKWTGVRNAKAYGPACISNSSVSTSPQKW---IDEDCLHINIFTSDKCLKSKDCAV 121

  Fly   120 MVYIHGGGFFSGSAHPMASGPEYLMDT---NKVVMVTMNYRLGPFGFLSTGDEHM-PGNFGFKDQ 180
            :.|.||||....||  :.....||:.|   ..|::....:|||.|......|:.: |.|....|.
 Worm   122 VTYFHGGGLMYDSA--VMFNDTYLLGTFVNQDVIIAIPAFRLGIFSHFVVEDQSIAPTNLALYDI 184

  Fly   181 RLALQWIQKHIATFGGDPKKVTVLGHSAGGISAHLHMISPNSK-----GLFQNSMSLTGTMFLSA 240
            .|.:::::..|..|||:.:|.|::|||.||  :.:::::.:||     .|||.|:.::.......
 Worm   185 LLGVEFVKNEIHNFGGNNQKNTIMGHSYGG--SIVNILTFSSKINHDLSLFQQSICMSSGHDFET 247

  Fly   241 MKILKDPLSQARRLGKELAIDQAESLSSQDLAEALRNVCPKKLLVSVDSLKVWDNMPHLTTLPVL 305
            ::|   .:.:..|..|.... ...|:..:.:.....::...|.|.:.|:|::      |....:|
 Worm   248 LEI---QIQKTNRFAKHAGC-TVPSIIEKKMTTRQSDLYRMKCLQNKDALEL------LRVQRLL 302

  Fly   306 E---APSPDAFLVEDPLDAHRAGRINQMPWILSLSSRAGEGSLFIMRAFINPK--------LRAE 359
            |   .|:....:..:||       |.::|:...:.|               ||        .|.|
 Worm   303 EDEGYPTYGYLVQREPL-------IQEIPYQEFMKS---------------PKKIPMLTGCTRYE 345

  Fly   360 FNENFLEH--------MALLLNLPEGTPVQMVSEILD-AYDFKGDSLNNDTMLKLAEISGDFNFY 415
                 ::|        .||....||...::...:..| .|:|...|  ::|...:.::.
 Worm   346 -----MDHSPAPKPIGQALGFENPEEVYMKFRKDWDDEVYEFGNHS--DETQAIMVQVR------ 397

  Fly   416 YPIYETISSYVTYANLEENPLFIYIFEFAGLNSITKFFAGTTDDYGLGAVHMDD-----GLHTIR 475
                      |...||....:..|::|:.               |...|.|.||     |:|.
 Worm   398 ----------VRVNNLLSKNVPAYLYEYT---------------YPKHARHTDDLFYLMGVHR-- 435

  Fly   476 IPVSFDDFPKDSEDAKVIQRMSSLMTDFAKTG 507
                   |.||..:.::.:...::..:|||.|
 Worm   436 -------FEKDENEIELGKVYETIFMNFAKFG 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	COesterase	31..508	CDD:278561	119/515 (23%)
		Aes	<106..>210	CDD:223730	31/108 (29%)
cest-4	NP_501043.1	Abhydrolase	28..503	CDD:389770	121/535 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810