Protein Alignment Jhedup and cest-5.2

DIOPT Version :9

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_501021.3
• Gene: cest-5.2 / 177428
• WormBaseID: WBGene00015284
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 569
• Identity: 129/569 - (22%)
• Similarity: 214/569 - (37%)
• Gaps: 162/569 - (28%)

  Fly    35 MPGYQSGEFEAFMGIPFAQPPVGPLRLKNPVPNEPWEGVLDAGAAKDSCIQRSYFAKEWGLMGVE 99
            :.|.|||:::.|..||||:||:|.||.:.|...|.|.||.:|.....:|:..|.:.:.......|
 Worm    31 LEGKQSGKYQLFRRIPFAKPPIGTLRFQKPESAEKWNGVWNATEYGPACMSNSTWTQSPQKWVDE 95

  Fly   100 DCLYLNVYRPKNRAEDK-LPVMVYIHGGGFFSGSAHPMASGPEYLMDT---NKVVMVTMNYRLGP 160
            |||::|::......:.| ..|:||||||.....||  :.....:|:::   ..|::|...:|||.
 Worm    96 DCLHVNIFTSDKCLKSKDCAVVVYIHGGEIVFDSA--VMFNDTFLLESFVKQDVILVIPAFRLGI 158

  Fly   161 FGFLSTGDEHM-PGNFGFKDQRLALQWIQKHIATFGGDPKKVTVLGHSAGGISAHLHMISP---N 221
            |...:..|::: |.|....|..||.::::..|..||||.:|:|:.|||.||..|.:...|.   .
 Worm   159 FSHFTVHDQNIAPNNLALYDIILAQEFVKSEIHNFGGDIQKITLFGHSYGGTIASMMAFSSEINQ 223

  Fly   222 SKGLFQNSMSLTGTMFLSAMKILKDPLSQARRLGK--------ELAIDQAESLSSQDLAEALRNV 278
            ...|||..:.::...:...   |::.:.::.|:.|        .||.....|...:.:.:.|:.:
 Worm   224 DLSLFQRIIVMSANQYFDT---LEEQIERSDRVVKHAGCSVPTNLARKMNRSQKEKYMMKCLQKL 285

  Fly   279 CPKKLLVSVDSLKV-----WDNM-------PHLTTLPVLEAPSPDAFLV-------EDPLDAHRA 324
            ...:||....||:.     ..|:       |.:|:|.:||:|.....|.       :|..:.|
 Worm   286 SGMELLSVQRSLEEAGYPDIGNLVLRGPLFPDVTSLEMLESPKMIPMLAGCTKFESDDEDETH-- 348

  Fly   325 GRINQMPWILSLSSRAGEGSLFIMRAF--INP-----KLRAEFNENFLEHMALLLNLPEGTPVQM 382
                                 ||.:.|  .||     |.|.:......:..    |..:.|...|
 Worm   349 ---------------------FIGKHFGLENPIECDEKYRKDLENGIFDRQ----NHSDKTQAIM 388

  Fly   383 VSEILDAYDFKGDSLNNDTMLKLAEISGDFNFYYPIYETISSYVTYANLEENPLFIYIFEFAGLN 447
            |                .|.|::.:                       |.::.:..|::||.
 Worm   389 V----------------PTKLRVDQ-----------------------LRKHGVPAYLYEFT--- 411

  Fly   448 SITKFFAGTTDDYGLGAVHMDD-----GLHTIRIPVSFDDFPKDSED---AKVIQRMSSLMTDFA 504
                        |...|.|.||     |:|         .|.||..:   .||.:.|......|.
 Worm   412 ------------YPKHAFHTDDLYYIMGIH---------PFEKDENEEHLEKVYRNMLINFIKFG 455

  Fly   505 KTGVFHEESICKVSDFKEQGMCNYLHFGGN---------KEKYLEDIRN 544
            :.|:..|     :||..|.   .|.....|         ::::.|:|.|
 Worm   456 EPGMGFE-----MSDLNES---TYFEIYWNETTGQKPRMRKRFEENITN 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	COesterase	31..508	CDD:278561	119/522 (23%)
		Aes	<106..>210	CDD:223730	33/108 (31%)
cest-5.2	NP_501021.3	Abhydrolase	23..498	CDD:389770	129/569 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156876
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740