Protein Alignment Jhedup and cest-25

DIOPT Version :9

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_497609.1
• Gene: cest-25 / 175390
• WormBaseID: WBGene00022178
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 510
• Identity: 148/510 - (29%)
• Similarity: 217/510 - (42%)
• Gaps: 102/510 - (20%)

  Fly    42 EFEAFMGIPFAQPPVGPLRLKNPVPNEPWEGVLDAGAAKDSCIQRSYFAKEWGLMGVEDCLYLN- 105
            :.:||.|||:|.||:|.||...|.|:|.|..|.:..:.....||:.:..........||.|.||
 Worm    38 QVDAFQGIPYAAPPIGNLRFALPQPHEKWTEVRETKSFGARGIQKDHVLSPKTSPQSEDNLTLNI 102

  Fly   106 ---VYRPKNRAEDKLPVMVYIHGGGFFSGSAHPMA--SGPEYLMDTNKVVMVTMNYRLGPFGFLS 165
               |:.|||  |...||::|||||||.|.|||...  |..::|: |..||:||:.||||..||.:
 Worm   103 FTPVWTPKN--ETGFPVILYIHGGGFVSDSAHKYGDMSICQHLV-TKDVVVVTIQYRLGFLGFWT 164

  Fly   166 TGDEHMPGNFGFKDQRLALQWIQKHIATFGGDPKKVTVLGHSAGGISAHLHMISPNSKGLFQNSM 230
            |||..:|.|....|...||:|::::|..|.|||..:|::|.||||.|.....|||.|:.|||..:
 Worm   165 TGDSSIPDNVALHDMVFALKWVKENIGLFNGDPNNITLMGQSAGGASVDFLSISPVSRDLFQKVI 229

  Fly   231 SLTGTMFLSAMKILKDPLSQARRLGKELAIDQAESLSSQDLAEALRNVCPKKLLVSVDSLKVWDN 295
            .:.|....| ..|...||:..|...:|:.:  .:.:::.|..|.||.: |.....|..:::..|.
 Worm   230 PMGGNASCS-WAIHPRPLNACRNRAQEIGV--FDGMNTLDWVEKLREL-PADKFASALNMEAVDT 290

  Fly   296 MPHLTTLPVLEAPSPDAFLVEDPL-----DAHRAGRINQMPWILSLSSRAGEGSLFI-------- 347
            .   |...:|..|..|...:..|:     :|....|:        |.....||.:|.
 Worm   291 K---TDPELLIGPKYDNLFIPRPVMELRKEAPMKPRL--------LGCAKSEGLVFAFFGLNTKH 344

  Fly   348 --------MRAFINPKL----RAEFNENFLEHMALLLNLPEGTPVQMVSEILDAYDFKGDSLNND 400
                    :.|.::.||    ..::.|..||.:     :..||............|.||||..|
 Worm   345 PLHAVQQDVSAILSEKLFPLKARDYQEKALEKL-----IEIGTDHSKEEWQRAMVDLKGDSFLN- 403

  Fly   401 TMLKLAEISGDFNFYYPIYETISSYVTYANLEENPLFIYIFEFAGLNSITKFFAGTTDDYGL--- 462
                    .|.......:.||..|         .|:::|.|::....:           ||:
 Worm   404 --------VGIQQNVLDVLETQPS---------TPIYMYSFDYCNPKA-----------YGIMGF 440

  Fly   463 -----GAVHMDD-----GLHTIRIPVSFDDFPKDSEDAKVIQRMSSLMTDFAKTG 507
                 .|.|..|     |.|.:.   |||   .:.||.|:|:..:.|.|:|||.|
 Worm   441 KLPFKDATHCTDISYVVGNHIVN---SFD---FNEEDYKMIEITTRLWTNFAKYG 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	COesterase	31..508	CDD:278561	148/510 (29%)
		Aes	<106..>210	CDD:223730	49/105 (47%)
cest-25	NP_497609.1	COesterase	18..536	CDD:365897	148/510 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810