Protein Alignment Jhedup and ace-4

DIOPT Version :9

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_496962.1
• Gene: ace-4 / 175074
• WormBaseID: WBGene00000038
• Length: 602
• Species: Caenorhabditis elegans
• Alignment Length: 650
• Identity: 179/650 - (27%)
• Similarity: 274/650 - (42%)
• Gaps: 157/650 - (24%)

  Fly     4 AGFGVLLFVAVAVGDSLD----VCLE-DMGCMRGTLMPGYQSGEFEAFMGIPFAQPPVGPLRLKN 63
            |.|...:|:.|.: ||:.    |.|| .:|.::||.. .:.|.:...|.|:|||:|.|...|.:.
 Worm     6 AFFAFFIFITVFI-DSVQAVHPVVLETKLGDIKGTEF-FFLSKKIRTFFGVPFAEPAVEDFRFRK 68

  Fly    64 PVPNEPWEGVLDAGAAKDSCIQR--SYFAKEWG-------LMGVEDCLYLNVYRPKNRAEDKLPV 119
            |...:.|.|:.||....::|.|.  :|....||       ....|||||||::.|.:..  .|.|
 Worm    69 PREKKQWRGLYDATKPANACFQTRDNYNTSFWGSEMWNANTQISEDCLYLNIWAPADAY--NLTV 131

  Fly   120 MVYIHGGGFFSGSAHPMASGPEYLMDTNKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQRLAL 184
            ||:..||||:|||........:.|..|..|::|.:||||||||||..|....|||.|..||:|||
 Worm   132 MVWFFGGGFYSGSPSLSIYDGKALTSTQNVIVVNINYRLGPFGFLYLGHPDAPGNMGLLDQQLAL 196

  Fly   185 QWIQKHIATFGGDPKKVTVLGHSAGGISAHLHMISPNSKGLFQNSMSLTGTMFLSAMKILKDPLS 249
            .|::::|.:|||:|.||.|.|.|||..|...|:|:|.|:|||:|::..:|:  |.....:..|..
 Worm   197 HWVRQNIVSFGGNPDKVAVFGQSAGAASIVAHLIAPGSRGLFKNAILQSGS--LENTWAINSPFR 259

  Fly   250 QARRLGKELAIDQAESLSSQDLAEALRNVCPKKLLVSVDSLKVWDNMPHLTTLPVLEAPSPDAFL 314
            ..::..|.|.:......:.......||.|.|::|     ||..|:     .:|..||.|    |:
 Worm   260 AKQKSEKLLELVGCNKTTVDTSMACLRLVSPEQL-----SLSTWN-----ISLTYLEFP----FV 310

  Fly   315 VED-------PLDAHRAGR-------INQMPWILSLSSRAGEG---SLFIMRAFIN----PKL-R 357
            :..       .||||.|.|       :|     |.:.....||   :::.:..|.:    |:| |
 Worm   311 IVSRDKHFFGHLDAHAALREGDFNRDVN-----LMIGMNKDEGNYWNIYQLPQFFDKADPPELNR 370

  Fly   358 AEF------------------------NENFLEHMALLLNLPEGTPVQ----MVSEILDAYDFKG 394
            .||                        :.|..:|         |...:    .:::|:..|.|..
 Worm   371 TEFDFLIDRTFSIQPDIIRSAAKYIYSDPNCTDH---------GRKTRFYAGQMNQIVGDYFFSC 426

  Fly   395 DSLNNDTMLKLAEISGDFNFYYPIYETISSYVTYANLEENPLFIYIFEFAGLNSITKFFAGTTDD 459
            ||      |.||:          .:.:|.. |..::.:..|..::::.|...:|...:...|
 Worm   427 DS------LWLAD----------QFRSIPR-VKSSSPQRKPGKVFVYHFTQSSSANPWPKWT--- 471

  Fly   460 YGLGAVHMDDGLHTIRIPVSFDDFPKDSE---DAKVIQRMSSLMTDFAKTGVFHEESICKVS--- 518
               ||:|..:..:...||:|:....|..|   ..|::|..:|    |||.|. .:..:.|.|
 Worm   472 ---GAMHGYEIEYVFGIPLSYSKNYKRREQIFSRKIMQFWAS----FAKNGT-PKLRVLKNSEHW 528

  Fly   519 -DFKEQGMCNY--LHFGGN----KEK------------------YLEDIRNSITLTAFPIWKKLF 558
             :|.||....:  |..|.|    |.|                  ||....:|.:||.:..|..|:
 Worm   529 PEFNEQNHYRWMQLRSGSNIRPIKPKKQVECQFWRRVKDTEYTAYLTQEYSSSSLTTYSYWLLLY 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	COesterase	31..508	CDD:278561	151/538 (28%)
		Aes	<106..>210	CDD:223730	48/103 (47%)
ace-4	NP_496962.1	COesterase	28..562	CDD:278561	165/594 (28%)
		Aes	<120..>243	CDD:223730	58/124 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156958
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840