Protein Alignment Jhedup and Nlgn1

DIOPT Version :9

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: XP_038957495.1
• Gene: Nlgn1 / 116647
• RGDID: 621117
• Length: 863
• Species: Rattus norvegicus
• Alignment Length: 678
• Identity: 175/678 - (25%)
• Similarity: 263/678 - (38%)
• Gaps: 191/678 - (28%)

  Fly    17 GDSLDVCLEDMGCMRGTL--------------------MPGYQS-------GEFEAFMGIPFAQP 54
            |..|.:||  :||:..|.                    :.|.:.       |....|:|:|:|.|
  Rat    26 GAPLTLCL--LGCLLQTFHVLSQKLDDVDPLVTTNFGKIRGIKKELNNEILGPVIQFLGVPYAAP 88

  Fly    55 PVGPLRLKNPVPNEPWEGVLDAGAAKDSCIQR-----------------------SYFAKEWGLM 96
            |.|..|.:.|.|..||..:.:|......|.|.                       ||...:
  Rat    89 PTGEHRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQ---- 149

  Fly    97 GVEDCLYLNVYRP------------------------------------KNRAEDK--------L 117
             .|||||||:|.|                                    .:||||:        .
  Rat   150 -SEDCLYLNIYVPTEDVKRISKECARKPGKKICRKGGPLTKTQTDDLGDNDRAEDEDIRDSGGPK 213

  Fly   118 PVMVYIHGGGFFSGSAHPMASGPEYLMDTNKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQRL 182
            |||||||||.:..|:.: :..| ..|.....|:::|:|||||..|||||||:...||:|..|...
  Rat   214 PVMVYIHGGSYMEGTGN-LYDG-SVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQ 276

  Fly   183 ALQWIQKHIATFGGDPKKVTVLGHSAGGISAHLHMI---------SPNSKGLFQNSMSLTGTMFL 238
            ||:|..::|..|||||.::||.|..|||...:|..:         |.::|||||.:::.:||. |
  Rat   277 ALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTA-L 340

  Fly   239 SAMKILKDPLSQARRLGKELAIDQAESLSSQDLAEALRNVCPKKLLVSVDSLKVWDNMPHLTTLP 303
            |:..:...|...||.|..::..:.::::   :|.|.|:.. |.|.||..|   |.....|:...|
  Rat   341 SSWAVSFQPAKYARILATKVGCNVSDTV---ELVECLQKK-PYKELVDQD---VQPARYHIAFGP 398

  Fly   304 VLEAPSPDAFLVEDPLDAHRAGRINQMPWILSLSSRAGEGSLFIMRAFINPK--LRAEFN---EN 363
            |::..    .:.:||......|..  :.:.:.|....|||..|:.....:..  ..::|:   .|
  Rat   399 VIDGD----VIPDDPQILMEQGEF--LNYDIMLGVNQGEGLKFVENIVDSDDGVSASDFDFAVSN 457

  Fly   364 FLEHMALLLNLPEGTPVQMVSEILDAYDFKGDSLNNDTMLK-LAEISGDFNFYYPIYETISSYVT 427
            |:::   |...|||..| :...|...|....|..|.:|..| |..:..|..:..|...|
  Rat   458 FVDN---LYGYPEGKDV-LRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVAT------ 512

  Fly   428 YANLEEN---PLFIYIFEFAGLNSITKFFAGTTDDY--GLGAVHMDDGLHTIRIPV--SFDDFPK 485
             |:|..|   |.:.|.|          :....||..  ...|.|.|:..:.:.||:  ..:.||.
  Rat   513 -ADLHSNFGSPTYFYAF----------YHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPC 566

  Fly   486 D--SEDAKVIQRMSSLMTDFAKTG------------------VFHEESICKVSDFKEQGMCNYLH 530
            :  ..|..:...:.:..|:|||||                  .|.|.:..:.|. |:|   .|||
  Rat   567 NFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQ-KDQ---LYLH 627

  Fly   531 FGGNKEKYLEDIR-NSITLTAFPIWKKL 557
            . |.|.:..|..| |.:.|     |.:|
  Rat   628 I-GLKPRVKEHYRANKVNL-----WLEL 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	COesterase	31..508	CDD:278561	153/612 (25%)
		Aes	<106..>210	CDD:223730	49/147 (33%)
Nlgn1	XP_038957495.1	COesterase	52..646	CDD:395084	166/645 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336126
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840