Protein Alignment Jhedup and Ache

DIOPT Version :9

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: XP_036020624.1
• Gene: Ache / 11423
• MGIID: 87876
• Length: 616
• Species: Mus musculus
• Alignment Length: 531
• Identity: 152/531 - (28%)
• Similarity: 230/531 - (43%)
• Gaps: 109/531 - (20%)

  Fly    28 GCMRGTLM--PGYQSGEFEAFMGIPFAQPPVGPLRLKNPVPNEPWEGVLDAGAAKDSCIQRSYFA 90
            |.:||..:  ||   |...||:|||||:||||..|...|.|..||.|||||...::.|.|  |..
Mouse    46 GQLRGIRLKAPG---GPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGVLDATTFQNVCYQ--YVD 105

  Fly    91 KEW-GLMGV----------EDCLYLNVYRPKNRAEDKLPVMVYIHGGGFFSGSAHPMASGPEYLM 144
            ..: |..|.          ||||||||:.|..|.....||:::|:||||:||:|........:|.
Mouse   106 TLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPASPTPVLIWIYGGGFYSGAASLDVYDGRFLA 170

  Fly   145 DTNKVVMVTMNYRLGPFGFLS-TGDEHMPGNFGFKDQRLALQWIQKHIATFGGDPKKVTVLGHSA 208
            .....|:|:||||:|.||||: .|....|||.|..||||||||:|::||.|||||..||:.|.||
Mouse   171 QVEGAVLVSMNYRVGTFGFLALPGSREAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESA 235

  Fly   209 GGISAHLHMISPNSKGLFQNSMSLTGT-----MFLSAMKILKDPLSQARRLGKELA--------- 259
            |..|..:|::|..|:.||..::..:||     ..:||        .:|||....||
Mouse   236 GAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSA--------GEARRRATLLARLVGCPPGG 292

  Fly   260 --------IDQAESLSSQDLAEALRNVCPKKLLVSVDSLKVWDNMPHLTTLPVLEAPSPDAFLVE 316
                    |....:..:|||.:...:|.|:            :::...:.:||::..    ||.:
Mouse   293 AGGNDTELIACLRTRPAQDLVDHEWHVLPQ------------ESIFRFSFVPVVDGD----FLSD 341

  Fly   317 DPLDAHRAGRINQMPWILSLSSRAGEGSLFIMRAFINPKLRAEFNENFLEHMALLLNLPEGTPVQ 381
            .|......|....:..::.:..  .|||.|::...  |....: ||:.:.....|..:..|.|
Mouse   342 TPEALINTGDFQDLQVLVGVVK--DEGSYFLVYGV--PGFSKD-NESLISRAQFLAGVRIGVP-- 399

  Fly   382 MVSEILDAYDFKGDSL----------NNDTMLK--LAEISGDFNFYYPIYETISSYVTYANLEEN 434
                  .|.|...:::          .:.|.|:  ::.:.||.|...|:.:.......    :..
Mouse   400 ------QASDLAAEAVVLHYTDWLHPEDPTHLRDAMSAVVGDHNVVCPVAQLAGRLAA----QGA 454

  Fly   435 PLFIYIFEFAGLNSITKFFAGTTDDYGLGAVH---MDDGLHTIRIPVSFDDFPKDSEDAKVIQRM 496
            .::.||||..........:.|....|.:..:.   :|..|:            ..:|:....||:
Mouse   455 RVYAYIFEHRASTLTWPLWMGVPHGYEIEFIFGLPLDPSLN------------YTTEERIFAQRL 507

  Fly   497 SSLMTDFAKTG 507
            ....|:||:||
Mouse   508 MKYWTNFARTG 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	COesterase	31..508	CDD:278561	151/528 (29%)
		Aes	<106..>210	CDD:223730	51/104 (49%)
Ache	XP_036020624.1	COesterase	37..563	CDD:395084	152/531 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832817
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840