DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jhedup and LOC107987423

DIOPT Version :9

Sequence 1:	NP_611085.2	Gene:	Jhedup / 36779	FlyBaseID:	FBgn0034076	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	XP_016885725.1	Gene:	LOC107987423 / 107987423	-ID:	-	Length:	286	Species:	Homo sapiens

Alignment Length:	284	Identity:	60/284 - (21%)
Similarity:	91/284 - (32%)	Gaps:	93/284 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   352 INPKLRAEFNENFLEHMALLLNLPEGTPVQMVSEILDAYDFKGDSLNNDTMLKL-AEISGDFNFY 415
            :..|...|..|..|:...|.|:| :|.|       .::....|..::...:||. .|:..:.||:
Human     5 LRQKTEEELLETTLKMKFLSLDL-QGDP-------RESQPLLGTVIDGMLLLKTPEELQAERNFH 61

  Fly   416 -----------------------YPIYETISSYVTYANL--EENPLFIYIFEFAGLNSITKFFAG 455
                                   ||:.|......|..:|  :..||.....|.  :...|:.:.|
Human    62 TVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKEL--IPEATEKYLG 124

  Fly   456 TTDD----------------YGLGAV-----HMDDGLHTIRIPVSF-DDFPKDSEDAKVI----- 493
            .|||                :|:.:|     |.|.|..|......: ..|..|.:...||
Human   125 GTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGD 189

  Fly   494 QRMSSLMTDFAKTGVFHEE-SICKV-----SDFKEQGMCN---------------YLHFGGNKE- 536
            :..|.....|.|.|...|| .:.|:     ::|...|..|               ||..|.|.:
Human   190 ELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQA 254

  Fly   537 -KYLEDIRNSITLTAFPIWKKLFA 559
             :.|:|..     .||  |..|||
Human   255 AQKLKDKE-----VAF--WTNLFA 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	COesterase	31..508	CDD:278561	41/208 (20%)
Jhedup	NP_611085.2	Aes	<106..>210	CDD:223730
LOC107987423	XP_016885725.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010