Protein Alignment Jhedup and nlgn1

DIOPT Version :10

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: XP_017949302.2
• Gene: nlgn1 / 100329186
• XenbaseID: XB-GENE-6041753
• Length: 859
• Species: Xenopus tropicalis
• Alignment Length: 683
• Identity: 176/683 - (25%)
• Similarity: 258/683 - (37%)
• Gaps: 187/683 - (27%)

  Fly     6 FGVLLFVAVAVGDSLD----VCLEDMGCMRG--------TLMPGYQSGEFEAFMGIPFAQPPVGP 58
            ||.||.:|......||    |.|...|.:||        .|.|..|      |:|:|:|.||:|.
 Frog    34 FGFLLHIATVRSQKLDDVDPVVLTTYGKVRGFKKELNNEILGPVVQ------FLGVPYAAPPIGE 92

  Fly    59 LRLKNPVPNEPWEGVLDAGAAKDSCIQR------------SYFAKEWGLMG------VEDCLYLN 105
            .|.:.|.|...|..:.::......|.|.            .:|.....::.      .|||||||
 Frog    93 RRFQPPEPPTMWGDIKNSTQFAPVCPQNIVGGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLN 157

  Fly   106 VYRP------------------------------------KNRAEDK--------LPVMVYIHGG 126
            :|.|                                    ...|||:        .|||||||||
 Frog   158 IYVPTEDVKRISKECARKPGKKICRKEGPLTKKQTDDLGDNEGAEDEDIRDSGGPKPVMVYIHGG 222

  Fly   127 GFFSGSAHPMASGPEYLMDTNKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQRLALQWIQKHI 191
            .:..|:.:....  ..|.....|:::|:|||||..|||||||:...||:|..|...||:|..::|
 Frog   223 SYMEGTGNVFDG--SVLASYGNVIVITVNYRLGVLGFLSTGDQASKGNYGLLDLIQALRWTSENI 285

  Fly   192 ATFGGDPKKVTVLGHSAGGISAHLHMI---------SPNSKGLFQNSMSLTGTMFLSAMKILKDP 247
            ..|||||.::||.|..||....:|..:         |.::|||||.:::.:||. ||:..:...|
 Frog   286 GFFGGDPLRITVFGSGAGASCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTA-LSSWAVSFQP 349

  Fly   248 LSQARRLGKELAIDQAESLSSQDLAEALRNVCPKKLLVSVDSLKVWDNMPHLTTLPVLEAPSPDA 312
            ...||.|..::..:.::   |.:|.|.|:.. |.:.||..|...|   ..|:...||::..
 Frog   350 AKYARILATKVGCNMSD---SGELVECLQKK-PYRELVDQDIQPV---RYHIAFGPVIDGD---- 403

  Fly   313 FLVEDPLDAHRAGRINQMPWILSLSSRAGEGSLFIMRAFINPK--LRAEFN---ENFLEHMALLL 372
            .:.:||......|..  :.:.:.|....|||..|:.....:..  ..::|:   .||:::   |.
 Frog   404 VIPDDPQVLMEQGEF--LNYDIMLGVNQGEGLKFVESTVDHEDGVSSSDFDFAVSNFVDN---LY 463

  Fly   373 NLPEGTPVQMVSEILDAYDFKGDSLNNDTMLK-LAEISGDFNFYYPIYETISSYVTYANLEEN-- 434
            ...||..: :...|...|....|..|.:|..| |..:..|..:..|...|       |:|..|
 Frog   464 GYTEGKDI-LRETIKFMYTDWADRNNPETRRKTLLALFTDHQWVAPAVAT-------ADLHSNFG 520

  Fly   435 -PLFIYIFEFAGLNSITKFFAGTTDDYGLGAVHMDDGLHTIRIPVSF--------DDFPKD--SE 488
             |.:.|.|          :....||.....|    |..|...||..|        :.||.:  ..
 Frog   521 SPTYFYAF----------YHHCQTDQVPAWA----DASHGDEIPYVFGIPMIGPTELFPCNFSKN 571

  Fly   489 DAKVIQRMSSLMTDFAKTG------------------VFHEESICKVSDFKEQGMCNYLHFGGN- 534
            |..:...:.:..|:|||||                  .|.|.:..:.|. |:|   .|||.|..
 Frog   572 DVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQ-KDQ---LYLHIGLKP 632

  Fly   535 --KEKY--------LE-----DIRNSITLTAFP 552
              ||.|        ||     .:.|.:|.|..|
 Frog   633 RVKEHYRATKVNLWLELVPRLHVMNDLTTTKGP 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	alpha/beta hydrolases	31..508	CDD:473884	148/592 (25%)
nlgn1	XP_017949302.2	COesterase	52..646	CDD:395084	163/644 (25%)