Protein Alignment Jhedup and ces2

DIOPT Version :10

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_001120019.1
• Gene: ces2 / 100144981
• XenbaseID: XB-GENE-6467140
• Length: 557
• Species: Xenopus tropicalis
• Alignment Length: 569
• Identity: 159/569 - (27%)
• Similarity: 247/569 - (43%)
• Gaps: 143/569 - (25%)

  Fly    46 FMGIPFAQPPVGPLRLKNPVPNEPWEGVLDAGAAKDSCIQ--------RSYFAKEWGLMGV-EDC 101
            |||:|||:||:||||.:.|.|.|||..|.:|.|....|:|        ..:|..::....| |||
 Frog    51 FMGVPFAKPPIGPLRFEAPQPPEPWSSVREATAPSPMCLQDKEVMELLADFFKAKFDFSRVSEDC 115

  Fly   102 LYLNVYRPKNRAEDK-LPVMVYIHGGG-------FFSGSAHPMASGPEYLMDTNKVVMVTMNYRL 158
            |||||:.|.::.|:. |||||:|||||       .|.|||         |.....||:|::.|||
 Frog   116 LYLNVFTPADKGENPGLPVMVFIHGGGLAIGGASMFEGSA---------LSAYENVVVVSIQYRL 171

  Fly   159 GPFGFLSTGDEHMPGNFGFKDQRLALQWIQKHIATFGGDPKKVTVLGHSAGGISAHLHMISPNSK 223
            |..|||||||:.:.|||||.||..||||::.:|..|||||:.||:.|.||||:|....::||.|:
 Frog   172 GIMGFLSTGDKEVRGNFGFLDQVAALQWVRDNIKDFGGDPQSVTIFGESAGGLSVSALVLSPLSE 236

  Fly   224 GLFQNSMSLTGTMFLSAMKILKD----PLSQARRLGKELAIDQAESLSSQDLAEALRNVCPKKLL 284
            |||..:::.:|...|..:...|.    ||       .::.|: ..|.|..||...|:|
 Frog   237 GLFHRAIAESGVAILPGLTASKTEEILPL-------LDMVIN-VSSCSVSDLVGCLKN------- 286

  Fly   285 VSVDSLKVWDNMPHLTT---LPVLEAPSPDAFLVEDPLDAHRAGRINQMPWILSLSSRAGEGSLF 346
                  |..|.:..:|.   ..:..|.....||.:...:...|...:.:|:::.::
 Frog   287 ------KTEDEIIEITAAMRYVIFPAVVDGVFLPKPAEEILAAKESHPVPFLIGIN--------- 336

  Fly   347 IMRAFINPKLRAEFNENFLEHMALLLNLP---EGTPVQMVSEILDAY---------------DFK 393
                          |..|...:.:.||:.   ||...:.:..||.|.               ::.
 Frog   337 --------------NHEFGSMLPVTLNITGYREGMEKKDIQAILGALPLLNTVSSVIPFIMEEYF 387

  Fly   394 GDSLNNDTMLK--LAEISGDFNFYYPIYETISSYVTYANLEENPLFIYIFEFAGLNSITKFFAGT 456
            ||: |:...|:  ..:::||..|..|...|...:      .::...:|.:||....|:   :|.:
 Frog   388 GDT-NDPKELRNNFLDLAGDIIFVIPALRTAKYH------RDSGFPVYFYEFQHRPSL---YADS 442

  Fly   457 TDDYGLGAVHMDD-----GLHTIRIPVSFDDFPKDSEDAKVIQR-MSSLMTDFAKTGVFHEESIC 515
            .:|: :.|.|.|:     |...::..:.|..  ..:|:.|::.: :.....:||:.|
 Frog   443 KEDF-VKADHGDELYFVGGGPFLKNGILFKS--NGTEEEKILSKTIMKYWANFARNG-------- 496

  Fly   516 KVSDFKEQGMCNYLHFGGNKEKYLEDIRNSITLT----------AFPIW 554
               |....|:..:..: ...|.|||     |.||          .|..|
 Frog   497 ---DPNGHGLAEWPKY-DEDEDYLE-----INLTQKSSQRLKGERFEFW 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	alpha/beta hydrolases	31..508	CDD:473884	147/511 (29%)
ces2	NP_001120019.1	COesterase	25..536	CDD:395084	158/567 (28%)