Protein Alignment Jhedup and nlgn2b

DIOPT Version :10

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_001159808.1
• Gene: nlgn2b / 100002407
• ZFINID: ZDB-GENE-090918-3
• Length: 860
• Species: Danio rerio
• Alignment Length: 597
• Identity: 156/597 - (26%)
• Similarity: 245/597 - (41%)
• Gaps: 136/597 - (22%)

  Fly    41 GEFEAFMGIPFAQPPVGPLRLKNPVPNEPWEGVLDAGAAKDSCIQRSYFAKEWGLMGV------- 98
            |..|.::|:|:|.||||..|.:.|.....|:.:.:|......|.|..:......::.|
Zfish    74 GPVEQYLGVPYATPPVGERRFQPPEAPGSWQEIRNATQFAPVCPQNIHGVLPEIMLPVWFTDNLD 138

  Fly    99 ----------EDCLYLNVYRP--------------KNRAED-------KLPVMVYIHGGGFFSGS 132
                      |||||||||.|              .||..|       |.|||::||||.|..|:
Zfish   139 AAAAYVQNQSEDCLYLNVYVPTEDGPLTKKHDESSMNRPRDEDIRDRRKKPVMLFIHGGSFMEGT 203

  Fly   133 AHPMASGPEYLMDTNKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQRLALQWIQKHIATFGGD 197
            .:...:  ..|.....|::||||||||..||||:||:...||:|..||..||:|:.::|..||||
Zfish   204 GNMFDA--SVLAAYGNVIVVTMNYRLGVLGFLSSGDQSAKGNYGLLDQIQALRWLNENIGHFGGD 266

  Fly   198 PKKVTVLGHSAGGISAHLHMISPNSKGLFQNSMSLTGTMFLSAMKILKDPLSQARRLGKELAIDQ 262
            |:::|:.|..||....:|.::|.:|:||||.:::.:|:. :|:..:...||...:.|.|::....
Zfish   267 PERITIFGSGAGASCVNLLILSHHSEGLFQRAIAQSGSA-ISSWSVNYRPLMYTKILAKKVGCSY 330

  Fly   263 AESLSSQDLAEALRNVCPKKLLVSVDSLKVWDNMP---HLTTLPVLEAP-SPDAFLVEDPLDAHR 323
            ::   :.||.:.||....::|   ||.    |..|   |:...||::.. .||     ||....:
Zfish   331 SD---TADLVDCLRRKSYREL---VDQ----DVQPARYHIAFGPVVDGDVVPD-----DPEILMQ 380

  Fly   324 AGRINQMPWILSLSSRAGEGSLFIMRAFINPKLRAEFNE---------------NFLEHMALLLN 373
            .|..  :.:.:.|....|||..|:           :.||               ||:::   |..
Zfish   381 QGEF--LNYDILLGVNQGEGLKFV-----------DDNEGEEGISAASFDYTISNFVDN---LYG 429

  Fly   374 LPEGTPVQMVSEILDAYDFKGDSLNNDTMLK-LAEISGDFNFYYPIYETISSYVTYANLEENPLF 437
            .|||..: :...|...|....|..|.|...| |..:..|..:..|...|...:..:    ::|::
Zfish   430 YPEGKDI-LRETIKFMYTDWADRDNGDMRRKTLLALFTDHQWVAPAVATAKLHAEF----QSPVY 489

  Fly   438 IYIFEFAGLNSITKFFAGTTDDYGLGAVHMDDGLHTIRIPV--SFDDFPKD--SEDAKVIQRMSS 498
            .|.|...........:|        .|.|.|:..:...:|:  :.:.||.:  ..|..:...:.:
Zfish   490 FYTFHHHCQTEARPEWA--------DAAHGDEIPYVFGVPMVGATELFPCNFSKNDIMLSAVVMT 546

  Fly   499 LMTDFAKTG------------------VFHEESICKVSDFKEQGMCNYLHFGGNKEKYLEDIRNS 545
            ..|:|||||                  .|.|....|.|...:|    |||.|....     ||::
Zfish   547 YWTNFAKTGDPNIPVPQDTKFIHTKPNRFEEVIWTKFSSKDKQ----YLHIGLKPR-----IRDN 602

  Fly   546 ITLTAFPIWKKL 557
            ........|.:|
Zfish   603 YRANKVAFWLEL 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	alpha/beta hydrolases	31..508	CDD:473884	143/546 (26%)
nlgn2b	NP_001159808.1	COesterase	52..611	CDD:395084	154/592 (26%)