DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Asph and Asphd1

DIOPT Version :9

Sequence 1:	NP_001261020.1	Gene:	Asph / 36778	FlyBaseID:	FBgn0034075	Length:	991	Species:	Drosophila melanogaster
Sequence 2:	XP_215083.2	Gene:	Asphd1 / 293498	RGDID:	1306636	Length:	360	Species:	Rattus norvegicus

Alignment Length:	279	Identity:	81/279 - (29%)
Similarity:	110/279 - (39%)	Gaps:	61/279 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   748 ESGEEGTQEAFFYLSLGETMQRLSMKSEALEVY------------------GKGVAKGF-FASLY 793
            ::|..|:.:.      ||..:...:.|..|..|                  |.|:..|. ...:.
  Rat    97 QTGSRGSGDP------GEGHRAEGLVSRRLRAYARRYSWAGMGRVRRAAQGGPGLTGGTGILGIQ 155

  Fly   794 QRSLYNEPRLRAQPFWQPKETGYERQLEKLTLNWRAI-RDEGLALLGRSGFFEDEAELLRDKGVW 857
            :..|...|.|.:.|| .|:: .....:|.|..::.|| ||.|..    |..|.....|.|.   |
  Rat   156 RPGLLFLPDLPSSPF-VPRD-AQRHDVELLQSSFPAILRDFGAV----SWDFSGSTPLPRG---W 211

  Fly   858 Q--------QYELYAQGRRVKDNCRRAPITCSLLEEFPESAGCRR-------GQVKFSVMQAKTH 907
            .        |..||..||....||||.|.....|.      |.|.       |...|||:.....
  Rat   212 SPPLAPGCYQLLLYQAGRCQPSNCRRCPGAYRALR------GLRSFMSANTFGNAGFSVLLPGAR 270

  Fly   908 VWPHCGPTNCRLRAHLTLAAPEPEKASLRVAEQERTWREGELFIFDDSFEHEVWHNGSQS---RL 969
            :...|||||.|:|.||.|..  |....|.|..:.:.|.||...:.||||.|.|.||||..   |:
  Rat   271 LEGRCGPTNARVRCHLGLKI--PPGCELVVGGEPQCWAEGHCLLVDDSFLHTVAHNGSPEDGPRV 333

  Fly   970 VLILDMWHPQLSAAQRRSL 988
            |.|:|:|||.::.|:|::|
  Rat   334 VFIVDLWHPNVAGAERQAL 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Asph	NP_001261020.1	TPR	610..854	CDD:223533	27/125 (22%)
		TPR repeat	684..714	CDD:276809
		TPR repeat	719..748	CDD:276809	81/279 (29%)
		TPR repeat	757..782	CDD:276809	5/42 (12%)
		Asp_Arg_Hydrox	826..977	CDD:282913	57/169 (34%)
Asphd1	XP_215083.2	Asp_Arg_Hydrox	184..341	CDD:282913	57/171 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350707
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3555
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740