DRSC/TRiP Functional Genomics Resources

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Protein Alignment Asph and ASPHD1

DIOPT Version :9

Sequence 1:NP_001261020.1 Gene:Asph / 36778 FlyBaseID:FBgn0034075 Length:991 Species:Drosophila melanogaster
Sequence 2:NP_859069.2 Gene:ASPHD1 / 253982 HGNCID:27380 Length:390 Species:Homo sapiens


Alignment Length:207 Identity:69/207 - (33%)
Similarity:90/207 - (43%) Gaps:36/207 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   801 PRLRAQPFWQPKETGYERQLEKLTLNWRAI-RDEGLALLGRSGFFEDEAELLRDKGVWQ------ 858
            |.|.:.|| .|:: .....:|.|..::.|| ||.|......||....      .:| |.      
Human   193 PDLPSAPF-VPRD-AQRHDVELLESSFPAILRDFGAVSWDFSGTTPP------PRG-WSPPLAPG 248

  Fly   859 --QYELYAQGRRVKDNCRRAPITCSLLEEFPESAGCRR-------GQVKFSVMQAKTHVWPHCGP 914
              |..||..||....||||.|.....|.      |.|.       |...|||:.....:...|||
Human   249 CYQLLLYQAGRCQPSNCRRCPGAYRALR------GLRSFMSANTFGNAGFSVLLPGARLEGRCGP 307

  Fly   915 TNCRLRAHLTLAAPEPEKASLRVAEQERTWREGELFIFDDSFEHEVWHNGSQS---RLVLILDMW 976
            ||.|:|.||.|..  |....|.|..:.:.|.||...:.||||.|.|.||||..   |:|.|:|:|
Human   308 TNARVRCHLGLKI--PPGCELVVGGEPQCWAEGHCLLVDDSFLHTVAHNGSPEDGPRVVFIVDLW 370

  Fly   977 HPQLSAAQRRSL 988
            ||.::.|:|::|
Human   371 HPNVAGAERQAL 382

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AsphNP_001261020.1 TPR 610..854 CDD:223533 14/53 (26%)
TPR repeat 684..714 CDD:276809
TPR repeat 719..748 CDD:276809
TPR repeat 757..782 CDD:276809
Asp_Arg_Hydrox 826..977 CDD:282913 56/169 (33%)
ASPHD1NP_859069.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..54
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 116..143
Asp_Arg_Hydrox 214..372 CDD:377460 57/172 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165156784
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG3555
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
43.700

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