Protein Alignment Asph and T24E12.10

DIOPT Version :10

• Sequence 1: NP_001261020.1
• Gene: Asph / 36778
• FlyBaseID: FBgn0034075
• Length: 991
• Species: Drosophila melanogaster
• Sequence 2: NP_494646.2
• Gene: T24E12.10 / 188866
• WormBaseID: WBGene00020777
• Length: 1318
• Species: Caenorhabditis elegans
• Alignment Length: 658
• Identity: 124/658 - (18%)
• Similarity: 223/658 - (33%)
• Gaps: 175/658 - (26%)

  Fly   108 DVQEPSGEALDDHDEHDDHDDHEDEEPLTEELEEELEEEEEPTEEDEPAADEEYEEDEDEENNAG 172
            ||..|..|.......|:...:.::..|| .|::.:||:::.         |....:|..|..|..
 Worm   197 DVVAPIAEPSSSSANHEASLEPQEVSPL-PEVQGDLEKDDH---------DHLLPDDSVEPQNGP 251

  Fly   173 ENITAEDAEEEEEEEDNDDEGTVEATVEATTEATTEATGEYEAEEDDEDEAAADDDAVESTEAPL 237
            .::..:..   |.|:.:|.|..|.:.|......:.|.       :||:.|.|.....  |:..|:
 Worm   252 TSLEVQGC---EAEDGHDHEFCVNSVVPQEPSPSPEV-------QDDQTEDAQQFSV--SSAVPI 304

  Fly   238 SKAEEQEDDEDEDEEEQEIEESVEPERSQYAAQSAPAKDNND----------DDDDDDQDKNDAD 292
            :.:..::|.:.|...|   .:|:|||     .|:..|||.:|          .:..:.|:..|.:
 Worm   305 APSIGKDDSQHEMSAE---VQSMEPE-----VQADFAKDFHDHVSCVNSVVPHEPVNSQEVQDYE 361

  Fly   293 DGDDDEFES-----LAQQFENDPEDTVPAKAVESEEQDQDQADEEEPKEEGSSWLASLAVKFGVG 352
            ..||::..:     :|:.|         :.|..||.|:..:..|.....:
 Worm   362 AEDDNDLSAQSVAPVAESF---------SSATTSEPQEIVEIQEHHAAHQ--------------- 402

  Fly   353 VALALVSRLVLIRKSPNTTEDEPAPETIFRRRLTIATAEDHIPDDVEELPPLDDEYSEEEIEIEE 417
              |..||.......|.|...||.:.|.....:.:|     |...:.||:....|.|:.....:|.
 Worm   403 --LPAVSVATFAETSDNKATDEMSMEAPDDHQFSI-----HWVSNFEEISFSPDGYNSLMDPLET 460

  Fly   418 EIEVEISDIEEEEEEVRHDNDDNVASMASYVPETFEQLSAMYKYAQEPTKDAKPEQKEKEPEKPV 482
            ....|:.|...|:   .||..|::...        ::||...|..:...:||.|
 Worm   461 SQSPEVRDYVNED---GHDFCDSLIKP--------KELSQSTKVREAQAEDAAP----------- 503

  Fly   483 GHSDIYVEYEDGAIEDYEHDGVSDEEITDEEDEISDVDDADLMNRLEAKYGRLPVKEFESDPDSD 547
                       ....:||....|||.:.:...|:.:                  .::|.|.|.|.
 Worm   504 -----------SVSPNYEASLASDEALCEIVVEVQE------------------DRQFSSSPASH 539

  Fly   548 DPSWTQIKPKEAAPAPAEKEDPFEQELRK-------------ANEEMIRENYAQALRSFNTLTTN 599
            |   ..|:.:|.:.:|..:.| .::|...             ||:|...|..|:...:....:..
 Worm   540 D---APIEQQETSQSPENQYD-IDEEAHHLSTQSVAPVKAFLANDETPHEISAEVHDNHQVESPE 600

  Fly   600 FAHEPSAHLGRARLLELLAKKERSNQRLWEAID--------AYKRYLAFGEL-VASNQEFQTAGE 655
            .:..|....|:|. :|.....:.:...|.|::.        |.::.....:: :|.....:.:.|
 Worm   601 PSPSPDVQNGQAE-IEQQYSADSAEPPLSESLKMAPVVEGRAAQQLSTVSDIPIAKPIPVKLSTE 664

  Fly   656 SCIEN----LRFLGHHRQATTIHELLINRLPEDPRLRNQLSLTYLMVNNLQQVEK--VAVETLKL 714
            :.:..    |.|..|....||.||.|:|.....|.               .||||  .:.:.:..
 Worm   665 TLLRQQGIPLNFPVHSIFPTTFHEALLNTCAGQPE---------------NQVEKQNFSFQAVPE 714

  Fly   715 WPNNAVAQ 722
            .|::|..|
 Worm   715 MPSSAEVQ 722

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Asph	NP_001261020.1	Spy	558..>762	CDD:443119	35/193 (18%)
		TPR repeat	684..714	CDD:276809	5/31 (16%)
		TPR repeat	719..748	CDD:276809	2/4 (50%)
		TPR repeat	757..782	CDD:276809
		Asp_Arg_Hydrox	826..978	CDD:461552
T24E12.10	NP_494646.2	None