Protein Alignment Ric and HRAS

DIOPT Version :10

• Sequence 1: NP_477211.1
• Gene: Ric / 36776
• FlyBaseID: FBgn0265605
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_005334.1
• Gene: HRAS / 3265
• HGNCID: 5173
• Length: 189
• Species: Homo sapiens
• Alignment Length: 168
• Identity: 89/168 - (52%)
• Similarity: 129/168 - (76%)
• Gaps: 1/168 - (0%)

  Fly    60 YKIVILGDGGVGKSAVTLQFVSHSFLDYHDPTIEDSYQQQAVIDNEAALLDILDTAGQVEFTAMR 124
            ||:|::|.|||||||:|:|.:.:.|:|.:||||||||::|.|||.|..||||||||||.|::|||
Human     4 YKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMR 68

  Fly   125 DQYMRCGEGFIICYSVTDRHSFQEASEYRKLITRVRLSEDIPLVLIANKVDLESQRRVTTEEGRN 189
            |||||.||||:..:::.:..||::..:||:.|.||:.|:|:|:||:.||.|| :.|.|.:.:.::
Human    69 DQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL-AARTVESRQAQD 132

  Fly   190 LANQFGCPFFETSAALRHYIDEAFYTLVREIRRKEMHK 227
            ||..:|.|:.||||..|..:::||||||||||:.::.|
Human   133 LARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRK 170

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ric	NP_477211.1	Rit_Rin_Ric	58..229	CDD:206712	89/168 (53%)
HRAS	NP_005334.1	H_N_K_Ras_like	3..164	CDD:133338	86/160 (54%)
		Effector region	32..40		6/7 (86%)
		Hypervariable region	166..185		1/5 (20%)