DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rho1 and RHO4

DIOPT Version :9

Sequence 1:	NP_477098.1	Gene:	Rho1 / 36775	FlyBaseID:	FBgn0014020	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_012981.3	Gene:	RHO4 / 853929	SGDID:	S000001763	Length:	291	Species:	Saccharomyces cerevisiae

Alignment Length:	198	Identity:	97/198 - (48%)
Similarity:	132/198 - (66%)	Gaps:	24/198 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIE-VDGKQVELALWDTAGQEDYDRLR 70
            |:|:|||||.|||||||.:.:..||..|:||:|||||.:|| .:|:.:|||||||||||:|.|||
Yeast    74 KIVVVGDGAVGKTCLLISYVQGTFPTDYIPTIFENYVTNIEGPNGQIIELALWDTAGQEEYSRLR 138

  Fly    71 PLSYPDTDVILMCFSVDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDPNTIRDLAKMK 135
            ||||.:.||:::|:||.|..||:|:.:.|.||||||||:.||:|||.|.||....| :.||
Yeast   139 PLSYTNADVLMVCYSVGSKTSLKNVEDLWFPEVKHFCPSTPIMLVGLKSDLYEADN-LSDL---- 198

  Fly   136 QEPVKPQEGRAMAEKINAFAYLECSAKSKEGVRDVFETATRAALQ------------VK---KRK 185
               |:|....::|:::.|||:::|||:.||.:.:|||||....|.            :|   ||.
Yeast   199 ---VEPSSAESLAKRLGAFAHIQCSARLKENIDEVFETAIHTLLSDSLYAPREPTHTIKNPFKRN 260

  Fly   186 KTR 188
            .||
Yeast   261 TTR 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rho1	NP_477098.1	RhoA_like	5..179	CDD:206662	91/172 (53%)
RHO4	NP_012981.3	Rho4_like	70..248	CDD:206704	92/181 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24072
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910