DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rho1 and RHOF

DIOPT Version :9

Sequence 1:	NP_477098.1	Gene:	Rho1 / 36775	FlyBaseID:	FBgn0014020	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_061907.2	Gene:	RHOF / 54509	HGNCID:	15703	Length:	211	Species:	Homo sapiens

Alignment Length:	191	Identity:	99/191 - (51%)
Similarity:	131/191 - (68%)	Gaps:	5/191 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRP 71
            |:||||||.||||.||:|:|:..|||.|.|:|||.|.|.:.|..|:|.|.|:|||||||||||||
Human    21 KIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQEDYDRLRP 85

  Fly    72 LSYPDTDVILMCFSVDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDPNTIRDLAKMKQ 136
            |||.:|.::|:|:.|.:|.|.:|:..||.|||.|||..:|::|:|.|.|||.|...:|.|...:.
Human    86 LSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDKEQLRKLRAAQL 150

  Fly   137 EPVKPQEGRAMAEKINAFAYLECSAKSKEGVRDVFETATRAAL----QVKKRKKTR-CLLL 192
            ||:...:|.:..|:|.|..|||||||.:|.|.|||..|.:.||    :.:::||.| ||||
Human   151 EPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVALSALKKAQRQKKRRLCLLL 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rho1	NP_477098.1	RhoA_like	5..179	CDD:206662	90/171 (53%)
RHOF	NP_061907.2	Rho4_like	17..211	CDD:206704	97/189 (51%)
		RHO	22..195	CDD:197554	91/172 (53%)
		Effector region. /evidence=ECO:0000255	48..56		5/7 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24072
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910