Protein Alignment Rho1 and RHOH

DIOPT Version :10

• Sequence 1: NP_477098.1
• Gene: Rho1 / 36775
• FlyBaseID: FBgn0014020
• Length: 192
• Species: Drosophila melanogaster
• Sequence 2: NP_004301.1
• Gene: RHOH / 399
• HGNCID: 686
• Length: 191
• Species: Homo sapiens
• Alignment Length: 184
• Identity: 77/184 - (41%)
• Similarity: 110/184 - (59%)
• Gaps: 7/184 - (3%)

  Fly     7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRP 71
            |.|:|||.|.|||.||:.|:.:.|||.|.|||:||...|:.:||.|:.|.||||||.:.:..:||
Human     6 KCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTAGNDAFRSIRP 70

  Fly    72 LSYPDTDVILMCFSVDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDPNTIRDLAKMKQ 136
            |||...||:|||:||.:.:|..|:..||..|::...|..|:::|..:.|.       |::...:.
Human    71 LSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQ-------REMGPHRA 128

  Fly   137 EPVKPQEGRAMAEKINAFAYLECSAKSKEGVRDVFETATRAALQVKKRKKTRCL 190
            ..|...||:.:|:.:.|..||||||.|..||:.|||.|.|.|:...:|:..|.|
Human   129 SCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRRRL 182

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rho1	NP_477098.1	RhoA_like	5..179	CDD:206662	73/171 (43%)
RHOH	NP_004301.1	Rho	5..169	CDD:206641	72/169 (43%)
		Effector region. /evidence=ECO:0000250	33..41		5/7 (71%)
		Interaction with ZAP70. /evidence=ECO:0000250	73..86		7/12 (58%)