Protein Alignment Rho1 and RND3

DIOPT Version :10

• Sequence 1: NP_477098.1
• Gene: Rho1 / 36775
• FlyBaseID: FBgn0014020
• Length: 192
• Species: Drosophila melanogaster
• Sequence 2: NP_005159.1
• Gene: RND3 / 390
• HGNCID: 671
• Length: 244
• Species: Homo sapiens
• Alignment Length: 191
• Identity: 94/191 - (49%)
• Similarity: 134/191 - (70%)
• Gaps: 6/191 - (3%)

  Fly     4 IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDR 68
            ::.|:|:|||..||||.||.||:||.|||.|||||||||.|..|:|.:::||:||||:|...||.
Human    22 VKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGSPYYDN 86

  Fly    69 LRPLSYPDTDVILMCFSVDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDPNTIRDLAK 133
            :|||||||:|.:|:||.:..|::|:::.:||..|::.||||..::|||.|.|||.|.:|:.:|:.
Human    87 VRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRTDVSTLVELSN 151

  Fly   134 MKQEPVKPQEGRAMAEKINAFAYLECSA-KSKEGVRDVFETATRAAL-----QVKKRKKTR 188
            .:|.||...:|..||::|.|..|:|||| :|:..|||:|..||.|.:     .||:.|..|
Human   152 HRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVNKTNKNVKRNKSQR 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rho1	NP_477098.1	RhoA_like	5..179	CDD:206662	90/174 (52%)
RND3	NP_005159.1	Rnd3_RhoE_Rho8	19..200	CDD:206735	90/177 (51%)
		Effector region. /evidence=ECO:0000255	52..60		7/7 (100%)