DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rho1 and Cdc42

DIOPT Version :9

Sequence 1:	NP_477098.1	Gene:	Rho1 / 36775	FlyBaseID:	FBgn0014020	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_001245762.1	Gene:	Cdc42 / 32981	FlyBaseID:	FBgn0010341	Length:	191	Species:	Drosophila melanogaster

Alignment Length:	193	Identity:	100/193 - (51%)
Similarity:	138/193 - (71%)	Gaps:	3/193 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTTIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQED 65
            |.||  |.|:|||||.|||||||.::.::||..||||||:||...:.:.|:...|.|:|||||||
  Fly     1 MQTI--KCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQED 63

  Fly    66 YDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDPNTIRD 130
            ||||||||||.|||.|:||||.||.|.||:.|||.||:.|.|...|.:|||.:.|||::.:|:..
  Fly    64 YDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCQKTPFLLVGTQIDLRDENSTLEK 128

  Fly   131 LAKMKQEPVKPQEGRAMAEKINAFAYLECSAKSKEGVRDVFETATRAALQ-VKKRKKTRCLLL 192
            |||.||:|:..::|..:|:::.|..|:||||.:::|:::||:.|..|||: .:..||.:|..|
  Fly   129 LAKNKQKPITMEQGEKLAKELKAVKYVECSALTQKGLKNVFDEAILAALEPPEPTKKRKCKFL 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rho1	NP_477098.1	RhoA_like	5..179	CDD:206662	91/173 (53%)
Cdc42	NP_001245762.1	Cdc42	3..177	CDD:206664	93/175 (53%)
Cdc42	NP_001245762.1	RHO	6..179	CDD:197554	92/172 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466338
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24072
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840