DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rho1 and rho2

DIOPT Version :9

Sequence 1:	NP_477098.1	Gene:	Rho1 / 36775	FlyBaseID:	FBgn0014020	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_594569.1	Gene:	rho2 / 2542773	PomBaseID:	SPAC16.01	Length:	200	Species:	Schizosaccharomyces pombe

Alignment Length:	193	Identity:	109/193 - (56%)
Similarity:	140/193 - (72%)	Gaps:	4/193 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDR 68
            ||:|||:|||||||||.||.||:...||..||||||||||:|..||||.|:||||||||||:|:|
pombe     7 IRRKLVVVGDGACGKTSLLSVFTLGYFPTEYVPTVFENYVSDCRVDGKSVQLALWDTAGQEEYER 71

  Fly    69 LRPLSYPDTDVILMCFSVDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDPNTIRDLAK 133
            |||:||....:||:.|::||||||||:..||..|:...|||||.||||.|.|||:||..|.::.:
pombe    72 LRPMSYAKAHIILVGFAIDSPDSLENVSTKWIEEINTLCPNVPFILVGMKADLRSDPVAIEEMRR 136

  Fly   134 MKQEPVKPQEGRAMAEKINAFAYLECSAKSKEGVRDVFETATRAALQVK----KRKKTRCLLL 192
            ..|..||.|:...:|::|.|..|:|||:.:.:||.||||.||||||.|:    .:..|:|.::
pombe   137 RNQNFVKSQQAELVAQRIGARKYMECSSLTGDGVDDVFEAATRAALTVRDSENDKSSTKCCII 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rho1	NP_477098.1	RhoA_like	5..179	CDD:206662	103/173 (60%)
rho2	NP_594569.1	Rho2	8..199	CDD:206702	108/190 (57%)
rho2	NP_594569.1	RHO	11..183	CDD:197554	102/171 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24072
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910