Protein Alignment Rho1 and Rhoa

DIOPT Version :10

• Sequence 1: NP_477098.1
• Gene: Rho1 / 36775
• FlyBaseID: FBgn0014020
• Length: 192
• Species: Drosophila melanogaster
• Sequence 2: NP_058082.2
• Gene: Rhoa / 11848
• MGIID: 1096342
• Length: 193
• Species: Mus musculus
• Alignment Length: 193
• Identity: 167/193 - (86%)
• Similarity: 181/193 - (93%)
• Gaps: 1/193 - (0%)

  Fly     1 MTTIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQED 65
            |..||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse     1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQED 65

  Fly    66 YDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDPNTIRD 130
            ||||||||||||||||||||:||||||||||||||||||||||||||||||||||||||.:|.|:
Mouse    66 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRE 130

  Fly   131 LAKMKQEPVKPQEGRAMAEKINAFAYLECSAKSKEGVRDVFETATRAALQVKK-RKKTRCLLL 192
            |||||||||||:|||.||.:|.||.|:|||||:|:|||:|||.|||||||.:: :||:.||:|
Mouse   131 LAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKKKSGCLIL 193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rho1	NP_477098.1	RhoA_like	5..179	CDD:206662	157/173 (91%)
Rhoa	NP_058082.2	RhoA_like	5..179	CDD:206662	157/173 (91%)
		Effector region. /evidence=ECO:0000255	34..42		7/7 (100%)
		Switch II region, involved in RAP1GDS1 isoform 3 binding. /evidence=ECO:0000250|UniProtKB:P61586	61..78		16/16 (100%)