Protein Alignment CG8414 and NOL9

DIOPT Version :9

• Sequence 1: NP_611084.2
• Gene: CG8414 / 36774
• FlyBaseID: FBgn0034073
• Length: 995
• Species: Drosophila melanogaster
• Sequence 2: NP_078930.4
• Gene: NOL9 / 79707
• HGNCID: 26265
• Length: 702
• Species: Homo sapiens
• Alignment Length: 634
• Identity: 146/634 - (23%)
• Similarity: 271/634 - (42%)
• Gaps: 115/634 - (18%)

  Fly   439 KENYLQPSDVPFYRNPQANPTELSVFEN-----SLKSNH-----------------VLAVIKEDL 481
            :.|...||.:|       :||..|..|:     |..|.|                 :|..:::..
Human    77 RPNTATPSPIP-------SPTPASEPESEPELESASSCHRPLLIPPVRPVGPGRALLLLPVEQGF 134

  Fly   482 EVYGTLVLTLLCGQISVNGYRARR----QEAITIYSPKGLNWVSI---SPTKTKKPVKDEVNWEE 539
            ...|...:|.|.||:.|.|:...:    |:..::|:...|:..::   .|.|:||.:|.|.
Human   135 TFSGICRVTCLYGQVQVFGFTISQGQPAQDIFSVYTHSCLSIHALHYSQPEKSKKELKREA---- 195

  Fly   540 LNKNFTRAQL---DR--IKTSFQRQTNAIVLLHRNTSAQQLVDTFGKHMAQNVFPLVNSSNRPFG 599
              :|..::.|   ||  ...:|..|.:.::|.|..|:....:.::    ..:.:..|..|..|..
Human   196 --RNLLKSHLNLDDRRWSMQNFSPQCSIVLLEHLKTATVNFITSY----PGSSYIFVQESPTPQI 254

  Fly   600 QSETL-LHCL-IQSSDQSRTLQVPQ----VWNKL------QMHATSRIIVAGGKGVGKSSLLRYL 652
            :.|.| |..: |:...:.:.||:.:    ...:|      ::.....|:|.|.:.||||:..|||
Human   255 KPEYLALRSVGIRREKKRKGLQLTESTLSALEELVNVSCEEVDGCPVILVCGSQDVGKSTFNRYL 319

  Fly   653 INRNLGQFPSMLLIDLDIGQPEIFVPQTISCTVIDEPLLGPGFLYNRQPEHAIVVGHTNIVLCAE 717
            ||..|...|.:..::.|:||.|...|..||...|.||:|||.|.:.|.|:..:..|..:   |..
Human   320 INHLLNSLPCVDYLECDLGQTEFTPPGCISLLNITEPVLGPPFTHLRTPQKMVYYGKPS---CKN 381

  Fly   718 QYARAVIQLVQNIQNDAKYSNIPWLINTMGYNKGFGIELMALLVDRIRPTDLVQIAS-------- 774
            .|.. .|.:|:.:.:..|..: |.::||||:....|:.|:..|:..:.|:.:||..|
Human   382 NYEN-YIDIVKYVFSAYKRES-PLIVNTMGWVSDQGLLLLIDLIRLLSPSHVVQFRSDHSKYMPD 444

  Fly   775 --PIPINNFDSVLDRNS---------LSQIKPIIYSAEEFKINEIPKYTLHKLISA-------VP 821
              |..:::.|.:..::.         |:.....:..|:|.|.:.: ::|.||||..       :.
Human   445 LTPQYVDDMDGLYTKSKTKMRNRRFRLAAFADALEFADEEKESPV-EFTGHKLIGVYTDFAFRIT 508

  Fly   822 AREKGTWSLSAKDMRYSNLLARLSSCLTGNAKSLTDCQPLGVSLE--SLKILH----PTSKNYS- 879
            .|.:.:.:...:|:...:.|::|...:......|....|..|...  :|:|.|    ||...|:
Human   509 PRNRESHNKILRDLSILSYLSQLQPPMPKPLSPLHSLTPYQVPFNAVALRITHSDVAPTHILYAV 573

  Fly   880 ---------REELIRGMEANVVYLCHHGAGLPQCLGIGVVRAIDYERKELYLVPAMPLQKMSLVD 935
                     .::.:||.....:.|..  ..:..|||.|:.|.||.|::..:::..:|.:::..|:
Human   574 NASWVGLCKIQDDVRGYTNGPILLAQ--TPICDCLGFGICRGIDMEKRLYHILTPVPPEELRTVN 636

  Fly   936 CLILGGEQSLPQGFLRDQGQGVSSSVPFVFILDDSKSSKSIQQIYHRAP 984
            ||::|. .::|...|:.| :|:..:||:|....:.|...:.::|..|.|
Human   637 CLLVGA-IAIPHCVLKCQ-RGIEGTVPYVTTDYNFKLPGASEKIGAREP 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8414	NP_611084.2	HC2	41..>163	CDD:284736
		RNA_pol_3_Rpc31	<255..333	CDD:288542
		P-loop_NTPase	639..824	CDD:304359	57/210 (27%)
NOL9	NP_078930.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	69..101		8/30 (27%)
		CLP1_P	306..>415	CDD:318723	39/113 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	680..702		2/4 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159395
Domainoid	1	1.000	72	1.000	Domainoid score	I9381
eggNOG	1	0.900	-	-		E1_COG1341
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	110	1.000	Inparanoid score	I4897
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005089
OrthoInspector	1	1.000	-	-		oto89772
orthoMCL	1	0.900	-	-		OOG6_103124
Panther	1	1.100	-	-	LDO	PTHR12755
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R523
SonicParanoid	1	1.000	-	-		X3611
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.780