Protein Alignment CG8414 and nol-9

DIOPT Version :9

• Sequence 1: NP_611084.2
• Gene: CG8414 / 36774
• FlyBaseID: FBgn0034073
• Length: 995
• Species: Drosophila melanogaster
• Sequence 2: NP_001255744.1
• Gene: nol-9 / 187190
• WormBaseID: WBGene00010709
• Length: 549
• Species: Caenorhabditis elegans
• Alignment Length: 559
• Identity: 117/559 - (20%)
• Similarity: 209/559 - (37%)
• Gaps: 110/559 - (19%)

  Fly   470 SNHVLAVIK--EDLEVYGTLVLTLLCGQISVNGYRARRQEAITIYSPKGLNWVSIS-PTKTKKPV 531
            ||..:.|::  |.|.::|:.....|.|..|:|.|.      :...|.:..|::.|| |.:...|.
 Worm    12 SNLEIYVVQPGERLSIFGSCSFLCLAGNASINDYN------LPAVSCESSNFMKISAPQRMDVPA 70

  Fly   532 KDEVNWEELNKNFTRAQLD-RIKTSFQRQTNAIVLLHRNTSA-----QQLVDTFGKHMAQNVFP- 589
            ..:|  .:...::..|:|. |:|....:....|:.:...|..     .:::| |.:.....|..
 Worm    71 ILQV--FKSGPSYKHARLKFRLKEVAPKNYEKIMEMIGTTEPSVFIFSKILD-FAEETVSGVVSN 132

  Fly   590 -LVNSSNRPFGQSETLL--HCLIQSSD-----QSRTLQVPQVWNKLQM----HATSRIIVAGGKG 642
             |::||.    |.:.:|  |..|...|     |.:..|:....|:|..    ...:.|:..|.||
 Worm   133 FLIHSSI----QKQIILPPHFFISRDDFIIYPQQQEAQLKSQMNRLNKLRNDGQRTTILPIGHKG 193

  Fly   643 VGKSSLLRYLINRNLGQ-FPSMLLIDLDIGQPEIFVPQTISCTVIDEPLLGPGFLYNRQP-EHAI 705
            .|||:|:|.|:||.|.. :..:.::|.||||.|......:|.|.:..|:||....:.|.. |::.
 Worm   194 AGKSNLMRSLVNRCLSNGYEHVYVLDCDIGQSEFTPCGCLSLTKVTSPILGKPHGHQRASFENSF 258

  Fly   706 VVGHTNIVLCAEQYARAVIQLVQNIQNDAKYSNIP---WLINTMGYNKGFGIELMALLVDRIRPT 767
            ..|...:     :.....:.:.:.:.|..|..:.|   .:||:||:....|.|::..:.....|.
 Worm   259 FYGDITV-----RDINLYMDIFERLFNKFKVISEPGSVCIINSMGWVTDEGAEILDGITRVTDPE 318

  Fly   768 DLVQIASPIPINNFDSVLDRNSLSQIKPIIYSAEE-----FKINEIPKYTLHKLISAVPAREKGT 827
            ..|:|.             |:........:..||.     |..|.|.       :..:|.:::
 Worm   319 LFVEIF-------------RDQTEARYQFLNRAEHNIVEIFANNSIG-------VIGLPPQKR-- 361

  Fly   828 WSLSAKDMRYSNLLARLSSCL-TGNAKSLTDCQPLGVSLESLKILHPTSKNYSREELIRGMEANV 891
              |.|..:|...::...||.| ..:..|.....|..:..|::.|..|.........:...:...:
 Worm   362 --LPAALIRELTIVGYFSSRLPRPSLASFPKVAPYKLRFENVTICVPVDLLVEDSHVFSSINTQI 424

  Fly   892 VYLCHHGAGLP-----------------------QCLGIGVVRAIDYERKELYLVPAMPLQKMSL 933
            :.||.:...|.                       ||:|.|::|.:..|.:.:::|..:.|.|:..
 Worm   425 MALCINNTDLKPRKLYGKDDLPSICVIDGNSPALQCIGFGIIRGVSVEERIIFVVTPVDLLKLEE 489

  Fly   934 VDCLILGGEQSLPQGF------------LRDQGQGVSSS 960
            ...|:.|.....|..|            |.|..||.|.:
 Worm   490 PPVLVRGMRIQTPTMFYTADPYNRCPYVLNDLEQGNSDN 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8414	NP_611084.2	HC2	41..>163	CDD:284736
		RNA_pol_3_Rpc31	<255..333	CDD:288542
		P-loop_NTPase	639..824	CDD:304359	45/194 (23%)
nol-9	NP_001255744.1	CLP1_P	190..376	CDD:293183	48/214 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167019
Domainoid	1	1.000	45	1.000	Domainoid score	I8317
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005089
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103124
Panther	1	1.100	-	-	LDO	PTHR12755
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R523
SonicParanoid	1	1.000	-	-		X3611
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.870