Protein Alignment CG8405 and tmem259

DIOPT Version :9

• Sequence 1: NP_001286475.1
• Gene: CG8405 / 36772
• FlyBaseID: FBgn0034071
• Length: 960
• Species: Drosophila melanogaster
• Sequence 2: NP_001072254.1
• Gene: tmem259 / 779707
• XenbaseID: XB-GENE-5753986
• Length: 627
• Species: Xenopus tropicalis
• Alignment Length: 738
• Identity: 309/738 - (41%)
• Similarity: 397/738 - (53%)
• Gaps: 146/738 - (19%)

  Fly     5 LPENAAEIAVANAINNINGNGNGNGRNRVLPGGLGGGGQNNMMNMRDRLFHAIYFRAAATYAELV 69
            :.||...|    .:||.||       |||....|   .||.::|:|||||||::|:.|.|||.|.
 Frog     1 MSENQGNI----PLNNANG-------NRVRTPNL---NQNPLINVRDRLFHALFFKMAVTYARLF 51

  Fly    70 PRKVQLTIEFLLLAKALLFFFTLIYVHNSFIKNPCTCLQDVK-NWPREGVIRVEIIPHLAEKRAI 133
            |...:...||.:|.||||..|.|.|:|.:|.::|..||:.|: .|||:|::||||  .|...||
 Frog    52 PPSFRRIFEFFVLLKALLVLFILAYIHIAFSRSPINCLEHVREKWPRDGILRVEI--QLNSSRA- 113

  Fly   134 WQGIKRDQEIVRSLKDS-YYYGI-----GPQTRQNHE-TLKRYESILGKLGLPVRP--------- 182
                    .|.....|| .:.|:     |....:..| :::.|.:...|..|.:.|
 Frog   114 --------PIFLQFYDSDTFPGLVKEPSGEDEEEEEEMSVEMYHNSSIKFELDIEPKVFLKPSLE 170

  Fly   183 --TFAYSNESLYYYF-DAINILDTYDHPNAIQLKNEEDDEEQYIVEYSLEYGHLRLSSSTRKRLR 244
              |.|..|:|....| ||               .::...:|:||||||||||.||||.|||:||.
 Frog   171 SVTQASENQSQTLSFSDA---------------ASKVWPQEEYIVEYSLEYGFLRLSQSTRQRLN 220

  Fly   245 IPVLTVQLDPNTDKCFGDSLTRYLLKRLLGYDDLLMASVRTIAEQEENKGYLRNVITGEHYRFVS 309
            |||:.|.|||..|.||||..:|:||...|||||:||:||:.:||.|||||:||||::||||||||
 Frog   221 IPVMVVTLDPTRDLCFGDRFSRFLLDEFLGYDDILMSSVKALAENEENKGFLRNVVSGEHYRFVS 285

  Fly   310 MWWAAWSSYPAAFCVMLLFTFSVSMLLRYSHHQIFVFIVDLLQMLEYNVSARFPIAPLLTVILAL 374
            ||.|. :||.|||.:|::||.|||||||||||||||||||||||||.|:|..||.||||||||||
 Frog   286 MWMAR-TSYLAAFVIMVIFTLSVSMLLRYSHHQIFVFIVDLLQMLEMNMSIAFPAAPLLTVILAL 349

  Fly   375 VGMEAIMSEFFNDTTTAFYIILIVWIADQYDAICCHTSITKRHWLRFFYLYHFAFYAYHYRFSGQ 439
            |||||||||||||||||||||||||:|||||||||||:.:||||||||||||||||||||||:||
 Frog   350 VGMEAIMSEFFNDTTTAFYIILIVWLADQYDAICCHTNTSKRHWLRFFYLYHFAFYAYHYRFNGQ 414

  Fly   440 YRTLALLSSYLFTQHSMVFFFHRYELPAIMAQHQV-FIITRNQGAAAAAAAAAAGAGGAEAAGGG 503
            |.:|||::|:||.||||::|||.||||||:.|.:: .::.:||.|
 Frog   415 YSSLALVTSWLFIQHSMIYFFHHYELPAILQQIRIQEMLLQNQQA-------------------- 459

  Fly   504 AGAGAAAGGQQGDGGAGGGGIGAGQQASMQRARLIVTRLFSQLAAQ-RHQQEPRPPGPTAAVGVA 567
                    ||              .|.|:|      ..|.:..|:: .....|:.||..:.
 Frog   460 --------GQ--------------NQTSLQ------DNLNNNTASEPSGATPPQAPGDPSH---- 492

  Fly   568 LANLRRLPVVGQLLQGREQFATVRRVFLGHGGNARLMQVRLQRINVADIPGLRNQVAAAM--AAA 630
                   |.||      ..::|.         ...|..|.|:     ::.|...||...:  ||.
 Frog   493 -------PPVG------SDYSTT---------EGALSDVLLE-----EVTGTSQQVVTGILPAAD 530

  Fly   631 GAAQRGQSAATDEPTIGDVATT-DVAAAADAAATPAANDAADVETNQGRKQPTTSSIND-AVATG 693
            ..||.|....|..|.|..|..| |.....:.:......|..:::..........||:.. |:...
 Frog   531 ERAQEGVCVGTHTPEIAAVTQTGDPPPVLNVSHNSCLTDQTELQGGMVSPIIDLSSLRSLAINLE 595

  Fly   694 AEGAQDKPGQEKVEVVENSGQEN 716
            :|.:........::.||.:.|.|
 Frog   596 SEQSSHTIAASALQCVEPTSQIN 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8405	NP_001286475.1	Membralin	44..416	CDD:286789	209/391 (53%)
tmem259	NP_001072254.1	Membralin	26..391	CDD:370655	209/391 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	373	1.000	Domainoid score	I877
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006624
OrthoInspector	1	1.000	-	-		oto104659
Panther	1	1.100	-	-	LDO	PTHR21650
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4352
SonicParanoid	1	1.000	-	-		X5625
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.130