Protein Alignment CG8405 and tmem259

DIOPT Version :9

• Sequence 1: NP_001286475.1
• Gene: CG8405 / 36772
• FlyBaseID: FBgn0034071
• Length: 960
• Species: Drosophila melanogaster
• Sequence 2: XP_005156017.1
• Gene: tmem259 / 571445
• ZFINID: ZDB-GENE-080225-14
• Length: 694
• Species: Danio rerio
• Alignment Length: 795
• Identity: 313/795 - (39%)
• Similarity: 411/795 - (51%)
• Gaps: 202/795 - (25%)

  Fly    16 NAINN---INGNGNGNGRNRVLPGGLGGGGQNNMMNMRDRLFHAIYFRAAATYAELVPRKVQLTI 77
            |..||   :|.|.|| |.||:....:   .||.::|:|||||||::|:.|.|||.|.|...:...
Zfish     7 NVNNNNVPLNNNNNG-GPNRIRNPPM---NQNPLINVRDRLFHALFFKMAVTYARLFPPSFRRIF 67

  Fly    78 EFLLLAKALLFFFTLIYVHNSFIKNPCTCLQDVK-NWPREGVIRVEIIPHLAEKRAIWQGIKRD- 140
            |||:|.|||...|.|.|:|.:|.::|..||:.|: .|||:|::||||..:.:......|..:.:
Zfish    68 EFLVLLKALFMLFILAYIHIAFSRSPINCLEHVREKWPRDGILRVEIQRNSSRAPIFLQFYETEG 132

  Fly   141 -QEIVRSLKDSYYYGIGPQTRQNHETLKRYESILGKLGLPVRPTFAYSNESLYYYFDAINILDTY 204
             |.:|:..::.     |.:.||                 ||.||.|...|.:        .:|.:
Zfish   133 IQGLVKEPEED-----GHENRQ-----------------PVVPTDAEEEEEM--------TMDMF 167

  Fly   205 DHPNAIQLK--------------------NEEDD------------------------------E 219
            |: :.::.:                    ||..|                              :
Zfish   168 DN-STVRFELDIEPRLNPSMSGGVPGSSLNESQDLSFSQTASKGMQPLRETVSEIEMLTRAVWPQ 231

  Fly   220 EQYIVEYSLEYGHLRLSSSTRKRLRIPVLTVQLDPNTDKCFGDSLTRYLLKRLLGYDDLLMASVR 284
            |:||||||||||.||||.:||:||.|||:.|.|||..|:||||..:|:||...|||||:||:||:
Zfish   232 EEYIVEYSLEYGFLRLSQATRQRLNIPVMVVTLDPMKDQCFGDGFSRFLLDECLGYDDILMSSVK 296

  Fly   285 TIAEQEENKGYLRNVITGEHYRFVSMWWAAWSSYPAAFCVMLLFTFSVSMLLRYSHHQIFVFIVD 349
            .:||.|||||:||||::||||||||||.|. :||.|||.:|::||.|||||||||||||||||||
Zfish   297 ALAENEENKGFLRNVVSGEHYRFVSMWMAR-TSYLAAFVIMVIFTLSVSMLLRYSHHQIFVFIVD 360

  Fly   350 LLQMLEYNVSARFPIAPLLTVILALVGMEAIMSEFFNDTTTAFYIILIVWIADQYDAICCHTSIT 414
            ||||||.|::..||.|||||||||||||||||||||||||||||||||||:|||||||||||:.:
Zfish   361 LLQMLEMNMTIAFPAAPLLTVILALVGMEAIMSEFFNDTTTAFYIILIVWLADQYDAICCHTNTS 425

  Fly   415 KRHWLRFFYLYHFAFYAYHYRFSGQYRTLALLSSYLFTQHSMVFFFHRYELPAIMAQHQV-FIIT 478
            ||||||||||||||||||||||:|||.:|||::|:||.||||::|||.||||||:.|.:: .::.
Zfish   426 KRHWLRFFYLYHFAFYAYHYRFNGQYSSLALVTSWLFIQHSMIYFFHHYELPAILQQIRIQEMLL 490

  Fly   479 RNQGAAAAAAAA-----------AAGAGGAEAAGGGAGAGAAAGGQQGDGGAGGGGIGAGQQASM 532
            :||........|           ||.||.|.||     |...|.||.             |||:.
Zfish   491 QNQQVGQGNQTALQDNLNNNTSTAAPAGQANAA-----ANVNANGQD-------------QQAAQ 537

  Fly   533 QR------ARLIVTRLFSQLAAQRHQQEPRPPG------PTAAVGVALANLRRLPVVGQLLQGRE 585
            .:      :.|:|....|          ..|.|      ...|:|   .::..:|.:|..|
Zfish   538 DQPLLETHSGLVVNPSLS----------INPSGSDLDWMAEIAIG---PDVLSVPNLGDPL---- 585

  Fly   586 QFATVRRVFLGHGGNARLMQVRLQRINVADIPGLRNQVAAAMAAAGAAQRGQSAATDEPTIGDVA 650
                     |..||   :.:.......|.::.|..        .||..|.|..:....||:
Zfish   586 ---------LEPGG---IQEATSSSAVVTELCGPN--------TAGENQNGNISTASVPTV---- 626

  Fly   651 TTDVAAAADAAATPAANDAADVETNQGRKQPTTSSINDAVAT-----------GAEGAQDKPGQE 704
                    :|.....|..........|:|:..|:|.:.:|.:           ||....||
Zfish   627 --------NAKGRSCAQGLGPPGGGGGQKESETNSSSSSVTSHTDCRVVESRRGATDWDDK---- 679

  Fly   705 KVEVVENSGQENLQH 719
                |||..:.:..|
Zfish   680 ----VENKSENSDSH 690

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8405	NP_001286475.1	Membralin	44..416	CDD:286789	204/424 (48%)
tmem259	XP_005156017.1	Membralin	34..427	CDD:286789	204/424 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578173
Domainoid	1	1.000	370	1.000	Domainoid score	I859
eggNOG	1	0.900	-	-		E1_KOG2092
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	479	1.000	Inparanoid score	I1434
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006624
OrthoInspector	1	1.000	-	-		oto39193
orthoMCL	1	0.900	-	-		OOG6_108561
Panther	1	1.100	-	-	LDO	PTHR21650
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4352
SonicParanoid	1	1.000	-	-		X5625
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.780