DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SP2353 and VC5.2

DIOPT Version :9

Sequence 1:	NP_001286474.1	Gene:	SP2353 / 36771	FlyBaseID:	FBgn0034070	Length:	1361	Species:	Drosophila melanogaster
Sequence 2:	NP_504797.1	Gene:	VC5.2 / 179097	WormBaseID:	WBGene00020908	Length:	588	Species:	Caenorhabditis elegans

Alignment Length:	169	Identity:	42/169 - (24%)
Similarity:	60/169 - (35%)	Gaps:	51/169 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   670 FIALYLNDGFVEFAFDL----GSGPALVRSEHSLSLGQWHTIKISRTARLAVLKVDKHQEVLTIS 730
            |||.:|.|...|...||    |:|     |.|       ||         |.:.:.||.|:  ..
Worm   367 FIAHHLGDQVAEDIEDLRVAGGTG-----SSH-------HT---------AAMLLVKHNEI--AE 408

  Fly   731 SNGFWHLSLDQNLFVGGVNHVDRLPLDLKYKPFFVG----CIQRIDI----NGHSLGIVAEALGG 787
            :....|    |......|:...|:.||.....|..|    |.::..:    .|.:|||..|
Worm   409 AGALAH----QKRIEESVSICKRIYLDYDGSCFCNGRSTMCDEKTHVCQNCTGGTLGIQCE---- 465

  Fly   788 SNIGNCPHACVARPCGPLAECVPQMESYECRCSIHNERC 826
                .||........|   :|||.::. :|.|:.|:..|
Worm   466 ----KCPEDLRLDKTG---KCVPGLDP-DCFCNSHSYEC 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SP2353	NP_001286474.1	FXa_inhibition	53..82	CDD:291342
		LamG	404..555	CDD:238058
		EGF	583..612	CDD:278437
		LamG	625..774	CDD:238058	27/115 (23%)
		LamG	1205..1340	CDD:214598
VC5.2	NP_504797.1	NPA	188..301	CDD:293078
		NPA	310..429	CDD:293078	22/88 (25%)
		EGF_Lam	487..531	CDD:238012	4/10 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3509
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900