Protein Alignment SP2353 and Lamb2

DIOPT Version :10

• Sequence 1: NP_611082.2
• Gene: SP2353 / 36771
• FlyBaseID: FBgn0034070
• Length: 1361
• Species: Drosophila melanogaster
• Sequence 2: NP_032509.2
• Gene: Lamb2 / 16779
• MGIID: 99916
• Length: 1799
• Species: Mus musculus
• Alignment Length: 129
• Identity: 30/129 - (23%)
• Similarity: 46/129 - (35%)
• Gaps: 29/129 - (22%)

  Fly    24 KGSRHEQEKLLRVSSTLYVGNLSFYTTEEQIHELFSRCGDVRRIIMGLDKFKKTPCGFCFVEYYS 88
            :|..:||.|.:||......|.....:|            :|...|:..|:....|.....|:..:
Mouse   426 RGFDYEQMKSVRVCVKAQDGGSPPLST------------NVTLDIIIQDQNDNAPQVLYPVQTGA 478

  Fly    89 RLDAESAMRYINGTRLDDRIVRVDWDAG-----------------FIEGRQYGRGKTGGQVRDE 135
            .:.||...|..:...|..::|.||.|:|                 |..|.|.|..:|..||.|:
Mouse   479 SVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKLQKAPDRALFEVGLQNGEIRTVRQVTDK 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP2353	NP_611082.2	FXa_inhibition	53..82	CDD:464251	4/28 (14%)
		LamG	404..555	CDD:238058
		EGF	583..612	CDD:394967
		LamG	625..774	CDD:238058
		LamG	1205..1340	CDD:214598
Lamb2	NP_032509.2	Laminin_N	50..284	CDD:459653
		EGF_Lam	286..338	CDD:238012
		Laminin_EGF	350..401	CDD:395007
		Laminin_EGF	413..470	CDD:395007	12/55 (22%)
		Laminin_EGF	473..527	CDD:395007	11/53 (21%)
		EGF_Lam	524..565	CDD:238012	8/19 (42%)
		EGF_Lam	784..829	CDD:214543
		Laminin_EGF	832..880	CDD:395007
		Laminin_EGF	878..925	CDD:395007
		EGF_Lam	927..985	CDD:238012
		Laminin_EGF	987..>1029	CDD:395007
		Laminin_EGF	1039..1093	CDD:395007
		Laminin_EGF	1096..1144	CDD:395007
		Laminin_EGF	1144..1191	CDD:395007
		Domain II	1191..1410
		SMC_prok_B	<1204..1571	CDD:274008
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1339..1365
		Domain alpha	1411..1443
		Domain I	1444..1799
		Smc	<1446..>1787	CDD:440809
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1679..1701
		cc_LAMB2_C	1728..1799	CDD:411970