Protein Alignment SP2353 and LOC1274755

DIOPT Version :10

• Sequence 1: NP_611082.2
• Gene: SP2353 / 36771
• FlyBaseID: FBgn0034070
• Length: 1361
• Species: Drosophila melanogaster
• Sequence 2: XP_313947.5
• Gene: LOC1274755 / 1274755
• VectorBaseID: AGAMI1_006011
• Length: 853
• Species: Anopheles gambiae
• Alignment Length: 690
• Identity: 142/690 - (20%)
• Similarity: 242/690 - (35%)
• Gaps: 191/690 - (27%)

  Fly   193 YISAES-------INFNSESEGQEQQDVADFKAASTMLPSSVPPTPSRSTTRATAS----TTTTT 246
            ||..|:       ::|:...||....|     :.|.::..:||.......|...|:    ...||
Mosquito   255 YIFRENRWFLRGVVSFSGIREGTNYCD-----SFSYVVFMNVPYYAKWIGTEVDAARQELLQATT 314

  Fly   247 TTTRRSPTRAP--KQRVDVDYGEGDGSDDYSYSYKSDMSVYDDVNNNQL----NLRRNSKSQTYQ 305
            ||.      ||  ..|.|.|.||.|..:|..||.:.::      ...|.    .:..|.:::...
Mosquito   315 TTA------APLVSNRWDSDLGEDDYEEDDIYSLRMEL------EGEQFAVASRMAGNGRTKQSV 367

  Fly   306 QT-----SNTNTAKNRRKYPNVTSNKVQMHITRETNRLENISAAEPAVVGAAMTTDRSTPTCNLD 365
            :|     |.|.:.|...:..:.|....::.....|..:||    |..|.............|.:
Mosquito   368 RTVRCGQSVTLSCKRSARLAHKTIRWYRVENGERTFLIEN----ETLVYRDVRYQHAGEYWCQV- 427

  Fly   366 CGSDGI---CALEATAASSRCLCPFGKTGNGCQEDIRAHVPRFAKRSWLAFPALHGAYKHVQLRI 427
            .|.:|:   ..|:.|...                 :..|..:.|..|:..:.|:....:..|...
Mosquito   428 TGDNGVMHETGLQLTVTR-----------------VPIHFQQDANVSYAVYDAVVDNRRSSQFSF 475

  Fly   428 E--FRPESFDGIIL----LSG----------ERDDLTGDFMALLLNKGFVEFWFDCGSGVGSVRS 476
            |  ||....||::.    ::|          ||..||    ..::..|.:|..|
Mosquito   476 EMTFRTNDSDGLLFHKPPIAGVESWSFSLLLERSRLT----LRVVPPGQLEKVF----------- 525

  Fly   477 RETILLN----EWNSVIIYRHRWDAWLVLN-------HGTKVQGRSNGLFSRITFREPVFLGGIG 530
             .::.||    .|::|::..:.....:.|:       .|..:|.||:..|             |.
Mosquito   526 -RSVKLNLQPTRWHTVLVSSYDGKGLMALDGQYLLGFEGHLLQHRSDRFF-------------IA 576

  Fly   531 NITGLAKRLPLAEGFAGCIRRFVANEHDYKFTEHPLGDVINGFDIQDCST--------------- 580
            ::..|.     ..||:||:.|.:.|:.......    |.|...::..|||
Mosquito   577 SVPELR-----TVGFSGCVSRLMINDRVLDLER----DFIERVNVGQCSTCSAEECTADLCPGAQ 632

  Fly   581 --DKCVRYPCQHGGKCLPSD----QGAICLCPIGFVGDLCEIRMDLQVPAFNGSSFLRYAPLGDS 639
              ..|:.|.|.. |:|..||    :|.   |.:..|.....:|       |..:|:..|......
Mosquito   633 EQKSCINYVCSE-GRCDGSDVLRPEGD---CDLDAVAHTQGLR-------FQHNSYASYRSFLLV 686

  Fly   640 ALIWLELKVTLKPEQADGLILYSGPEHR---GDFIALYLNDGFVEFAF--DLGSGPALVRSEHSL 699
            ||. ::|:..|:... ||::|::. |||   |.||.:....|.:|..|  |.......:.|...|
Mosquito   687 ALT-VDLQFQLRSTN-DGIVLHAA-EHRRGFGKFITIVAKAGRLELRFTTDAHLHTIYLESSVKL 748

  Fly   700 SLGQWHTIKISRTARLAVLKVDKHQEVL-TISSNGFWHLSLDQNL--FVGGV-------NHVD-R 753
            :.|:|:.::.........|:||...||. ::....|   ..|:.|  |:|||       .|.| :
Mosquito   749 TTGRWYRLQAGYRDGYVYLQVDDELEVARSVLGTVF---PTDRQLIVFLGGVRWQGFINRHKDVK 810

  Fly   754 LPLDLKYKPFFVGCIQRIDINGHSLGIVAEALGGSNIGNC 793
            ..||        ||::...::|..:.:|.:.:..:|:.:|
Mosquito   811 QGLD--------GCVKEFKLSGLPVDLVDDMVESANVRSC 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP2353	NP_611082.2	FXa_inhibition	53..82	CDD:464251
		LamG	404..555	CDD:238058	34/177 (19%)
		EGF	583..612	CDD:394967	10/32 (31%)
		LamG	625..774	CDD:238058	42/164 (26%)
		LamG	1205..1340	CDD:214598
LOC1274755	XP_313947.5	None