DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment casp and AT4G23040

DIOPT Version :9

Sequence 1:	NP_611080.1	Gene:	casp / 36769	FlyBaseID:	FBgn0034068	Length:	695	Species:	Drosophila melanogaster
Sequence 2:	NP_567675.1	Gene:	AT4G23040 / 828403	AraportID:	AT4G23040	Length:	525	Species:	Arabidopsis thaliana

Alignment Length:	531	Identity:	116/531 - (21%)
Similarity:	199/531 - (37%)	Gaps:	171/531 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   243 FESDP----PLTLSLPGRMTVQEVKMNVFDIKSIPVRHQEWTGWPNGCDNDTTLAQSGIGLSHRF 303
            |::||    |..:|.|.            :.:.||:..::..| |:|..||....:.
plant    84 FDNDPVMSRPPFVSHPR------------EAREIPIEVKDSNG-PSGQSNDAPTIED-------- 127

  Fly   304 AVRSTERSAPTNSNQHNAFDVVTVDSESSTDEFEDATDFNNAEYIFTDSPPAQPPNRHLIP---- 364
            ...:.:...|.      |.:.|.:| |.|.|:.:.|             |..|  :||.:|
plant   128 VTETAQAHGPA------AQEAVIID-EVSDDDNQSA-------------PTGQ--SRHAVPVGSA 170

  Fly   365 -------NDTDDEISGSTQFVENYKARYGEPCPEFFVGSLENAKQLACLR------SAKER---K 413
                   ||.:::|..:.  :|..|...|:...:..  ::::|:: ..||      |:.||   :
plant   171 ENNMQHYNDIEEQIIRAA--IEASKMETGDDVTKSV--TVQSAER-EVLRSEGWKASSSEREASE 230

  Fly   414 LLAIYLHHGKSILSNVFC-----------------DQLMKHESIIQTFKEKFVLYGWDMTYESNK 461
            :::|.:..|....:..|.                 |.:.:.|..:.:.:.:..:.|
plant   231 MVSIPVQQGSRASNGRFAAPSSLSEDDDDDDDDDPDYVEEEEEPLVSHRPRRAVSG--------- 286

  Fly   462 DMFLSSLTACISSNASLTARNIKLDKLPAIMLVGKSRQLGSNCEVLSVIH------------GNI 514
                        |.:||.      |.||      :|.:...     :.||            |.|
plant   287 ------------SRSSLN------DDLP------RSPEAED-----ATIHSPGAGNGFPSEWGGI 322

  Fly   515 GLDDLLTRLIETCEMF----EEQLQVEIRQEDERAARDQ---------VKAEQDMAYQETLQADM 566
            ..::....::....||    |.:..|......:|..|..         ::.:||..|..:|:||.
plant   323 SSEEHDEAIMLEAAMFGGISESEYGVPYAHYPQRTQRPPSPSLTAQRLIREQQDDEYLASLEADR 387

  Fly   567 AKDAAKR-QKEAAQL-----AERKRMESERAEEDARRESIRLVAQQ-SLPQEPSEQETGTSKIRV 624
            .|..|:| ::|||::     |:||..|:.|..|:.:....:||::: ||||||...|.....::|
plant   388 VKAEARRLEEEAARVEAIEEAKRKEEEARRKVEEEQELERQLVSKEASLPQEPPAGEENAITLQV 452

  Fly   625 RKPTGDFLERRFFINNNLQDLLNF------VTANGFLIEEYKLISSWPRRDLTAIESSQTLESLK 683
            |.|.|....||||.::.||.|.:|      |..|     .|:|:..:|||.....|.|.||..:.
plant   453 RLPDGTRHGRRFFKSDKLQSLFDFIDICRVVKPN-----TYRLVRPYPRRAFGDGECSSTLNDIG 512

  Fly   684 L-YPQETVILE 693
            | ..||.:.||
plant   513 LTSKQEALFLE 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
casp	NP_611080.1	UBA_FAF1	12..44	CDD:270596
		UBL	148..>182	CDD:176364
		UAS_FAF1	392..530	CDD:239288	23/175 (13%)
		Faf1_UBX	616..695	CDD:176366	29/85 (34%)
AT4G23040	NP_567675.1	UBA_Ubx1_like	6..42	CDD:270536
AT4G23040	NP_567675.1	UBX	444..524	CDD:395637	29/85 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	42	1.000	Domainoid score	I4781
eggNOG	1	0.900	-	-		E1_KOG1363
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23322
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910