DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment casp and SAY1

DIOPT Version :9

Sequence 1:	NP_611080.1	Gene:	casp / 36769	FlyBaseID:	FBgn0034068	Length:	695	Species:	Drosophila melanogaster
Sequence 2:	NP_567380.2	Gene:	SAY1 / 826779	AraportID:	AT4G11740	Length:	564	Species:	Arabidopsis thaliana

Alignment Length:	538	Identity:	119/538 - (22%)
Similarity:	188/538 - (34%)	Gaps:	143/538 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   233 VDKDFTIFIQFESDP----PLTLSLPGRMTVQEVKMNVFDIKSIPVRHQEWTGWPNGCDNDTTLA 293
            :|.||...: |:|||    |..:|.|.            :::.||:..::.:| |:|..:|....
plant    91 LDSDFARRV-FDSDPLMPRPPFVSHPR------------EVRQIPIEVKDSSG-PSGRSSDAPTI 141

  Fly   294 QSGIGLSHRFAVRSTERSAPTNSNQHNAFDVVTVDSESSTDEFEDATDFNNAEYIFTDSPPAQPP 358
            :.....:|.....:|:             ..|.:|.||.                  |..|..|.
plant   142 EDVTETAHVQGPVTTQ-------------GTVIIDEESD------------------DDIPFAPM 175

  Fly   359 NRHLIPNDTDDEISGSTQFVENYKARYGEPCPEFFVGSLENAKQLACLRSAKERKLL---AIYLH 420
            .|     ...|..:||.  ..|....|.:...|....::|.:|:.|   ......||   .:::.
plant   176 GR-----SRQDRPAGSV--ANNNNQDYNDIEEEMIRAAIEASKKEA---EGSSNPLLEERPLHME 230

  Fly   421 HGKSILSNVFCDQLMKHESIIQTFKEKFVLYGWDMTYESNKDMFLSSLTAC------ISSNASLT 479
            ....|...|........|.::::...|          .|..::..|::||.      .:.|..|.
plant   231 DDDDIAIAVTMSLKSAEEEVLRSQGYK----------ASTSEIGASAVTAAQGPQDTQALNGRLA 285

  Fly   480 ARNI-------KLDKLPAIM--------------LVGKSRQLGSNCEVLSVIH------------ 511
            |.:.       .:|:.|.:.              ...:||. ||..|..:.|:
plant   286 APSSPFDDDSDDVDEQPLVRHRPRRAASGSLAPPNADRSRS-GSPEEEHASINPAERGSGFPSEW 349

  Fly   512 GNIGLDDLLTRLIETCEMF--------------EEQLQVEIR-QEDERAARDQVKAEQDMAYQET 561
            |.|..::....::....||              ..|.:.:.| ......|:..::.:||..|..:
plant   350 GGISSEEHDEAVMLEAAMFGGIPETGYNHLPFLPPQPRAQPRPPSPSLTAQRLIREQQDDEYVAS 414

  Fly   562 LQADMAKDAAK-RQKEAAQLAE---RKRM--ESERAEEDARR---ESIRLVAQ-----QSLPQEP 612
            ||||..|:... |..||.||.|   ||..  |.::.||:|:|   |...|..|     .|||:||
plant   415 LQADRDKEMKSIRDAEARQLEEETARKAFLEEEKKKEEEAQRKLEEEQELERQLDAKEASLPKEP 479

  Fly   613 SEQETGTSKIRVRKPTGDFLERRFFINNNLQDLLNFV-TANGFLIEEYKLISSWPRRDLTAIESS 676
            ...|.....:.:|.|.|....|||..::.||.|.||: .|.......|:|:..:||......||.
plant   480 QADEENAITLLIRMPDGTRRGRRFLKSDKLQTLFNFIDIARVVKPNTYRLVRPYPRHAFGDGESE 544

  Fly   677 QTLESLKL-YPQETVILE 693
            .||..|.| ..||.:.||
plant   545 STLNDLGLTSKQEALFLE 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
casp	NP_611080.1	UBA_FAF1	12..44	CDD:270596
		UBL	148..>182	CDD:176364
		UAS_FAF1	392..530	CDD:239288	26/179 (15%)
		Faf1_UBX	616..695	CDD:176366	27/80 (34%)
SAY1	NP_567380.2	UBA_Ubx1_like	6..42	CDD:270536
SAY1	NP_567380.2	UBX	483..563	CDD:279169	27/80 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	42	1.000	Domainoid score	I4781
eggNOG	1	0.900	-	-		E1_KOG1363
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23322
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910