DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment casp and AT4G10790

DIOPT Version :9

Sequence 1:	NP_611080.1	Gene:	casp / 36769	FlyBaseID:	FBgn0034068	Length:	695	Species:	Drosophila melanogaster
Sequence 2:	NP_192817.1	Gene:	AT4G10790 / 826675	AraportID:	AT4G10790	Length:	480	Species:	Arabidopsis thaliana

Alignment Length:	344	Identity:	89/344 - (25%)
Similarity:	160/344 - (46%)	Gaps:	47/344 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   371 ISGSTQFVENYKARYGEPCP---EFFVGSLENAKQLACLRSAKERKLLAIYLHHGKSILSNVFCD 432
            :..:.:||..:...||....   :|.|....:|.|    ||....|||.:|||......:.|||.
plant   161 VGEAMEFVALFDRDYGSNNAFKIDFVVEGFMDALQ----RSRSSFKLLFVYLHSPDHPDTPVFCG 221

  Fly   433 QLMKHESIIQTFKEKFVLYGWDMTYESNKDMFLSSLTACISSNASLTARNIKLDKLP--AIMLVG 495
            ..:.:|:::....|.||.:|..:.                ||.....:.::|..:.|  |:::..
plant   222 GTLCNEAVVAFVNENFVSWGGSIR----------------SSEGFKMSNSLKASRFPFCAVVMPA 270

  Fly   496 KSRQLGSNCEVLSVIHGNIGLDDLLTRLIETCEMFEEQLQVEIRQEDERAARDQVKAEQDMAYQE 560
            .::::.    :|..:.|....:::|..|....|.....|.....:.:||....:::.|||.||:.
plant   271 ANQRIA----LLQQVEGPKSPEEMLAILQRIVEDSSPTLVTARVEAEERRTNLRLREEQDAAYRA 331

  Fly   561 TLQADMAKDAAKR------QKEAAQLAERKRMESERAEEDARRES-------IRLVAQQSLP--Q 610
            .|:||.|::..::      ::|||: ||||..|.|.|.|.|.||:       :|:..:::|.  :
plant   332 ALEADQAREQQRQEEKERLEREAAE-AERKLKEEEEARERAAREAEERQAARVRMRQEKALALGE 395

  Fly   611 EPSEQETGTSKIRVRKPTGDFLERRFFINNNLQDLLNFVTANGFL-IEEYKLISSWPRRDLTAIE 674
            || |:....:::.||.|.|:...|.|.....:|.|.::|.:.|.| .|||.||:::||......:
plant   396 EP-EKGPDVTQVLVRFPNGERKGRMFKSETKIQTLYDYVDSLGLLDTEEYSLITNFPRTVYGRDK 459

  Fly   675 SSQTLESLKLYPQETVILE 693
            .|.:|:...|:||.::.:|
plant   460 ESMSLKDAGLHPQASLFIE 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
casp	NP_611080.1	UBA_FAF1	12..44	CDD:270596
		UBL	148..>182	CDD:176364
		UAS_FAF1	392..530	CDD:239288	30/139 (22%)
		Faf1_UBX	616..695	CDD:176366	24/79 (30%)
AT4G10790	NP_192817.1	UBA_FAF	11..42	CDD:270538
		UAS	173..295	CDD:214737	30/145 (21%)
		tolA_full	237..>362	CDD:274303	32/145 (22%)
		SPFH_like	<317..360	CDD:302763	14/43 (33%)
		UBX	398..478	CDD:279169	24/79 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	42	1.000	Domainoid score	I4781
eggNOG	1	0.900	-	-		E1_KOG1363
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23322
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.870