DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment casp and CG8892

DIOPT Version :9

Sequence 1:	NP_611080.1	Gene:	casp / 36769	FlyBaseID:	FBgn0034068	Length:	695	Species:	Drosophila melanogaster
Sequence 2:	NP_001260064.1	Gene:	CG8892 / 33719	FlyBaseID:	FBgn0031664	Length:	496	Species:	Drosophila melanogaster

Alignment Length:	366	Identity:	62/366 - (16%)
Similarity:	141/366 - (38%)	Gaps:	83/366 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   374 STQFVENYKARYGE----PCPEFFVGSLENAKQLACLRSAKERKLLAIYLH----HGKSILSNVF 430
            ||.......:|.|:    |....:.|||..|::.|    .|.::.|.:.:.    ..:::..:|:
  Fly   161 STTDTATSTSRLGDLFRPPTDILYSGSLTAAREFA----TKRQRWLLVNVQDENFQSQTLNRDVW 221

  Fly   431 CDQLMKHESIIQTFKEKFVLYGWDMTYESNKDMFLSSLTACISSNASLTARNIKLDKLPAIMLVG 495
            .|:.:|     :..:.:|..  |.:..::::.....:...|.:              ||.|.::.
  Fly   222 SDKELK-----KLIRRQFTF--WQVDNDTSEGRRFVAFYHCAT--------------LPYICVID 265

  Fly   496 --KSRQLGSNCEVLSVIHGNIGLDDLLTRLIETCEMFEEQLQVEIRQEDERAAR---DQVKAEQD 555
              ...::..:.|.        .|:::|..|.:..:...:.:|.:.....:|:|.   |....:.:
  Fly   266 PRTGEEVWRSAEP--------KLENILPDLRQFLKEHRDFIQEDAPGTSKRSATYIDDDEVPDPE 322

  Fly   556 MAYQETLQADMAKDAAKRQKEAAQLAERKRME----------------------------SERAE 592
            .:...|..   :|:..|::.:..:|.|.:::|                            ...:.
  Fly   323 ASCSSTAS---SKEMPKKRAKVLELTEEEQLELAIKNSINENGGGGGEGNQKNDSPDGASDNESL 384

  Fly   593 EDARRESIRLVAQQSLPQEPSEQETGTSKIRVR----KPTGDFLERRFFINNNLQDLLNFVTANG 653
            |:...|.::.||..|......|.:|..:.:::|    ..|.:.::.|:..:..||.|..:::...
  Fly   385 EEFDDEELKGVAAASFENHLGEAKTELTALKLRLLNAAGTDEMVQLRWPSDTKLQTLRLYISQTH 449

  Fly   654 FLIEE--YKLISSWPRRDLTAIESSQTLESLKLYPQETVIL 692
            ..|.:  ||||.::||:.|.|..:..:|:.|.|:|...:.|
  Fly   450 KHIPQDGYKLICAFPRKFLEAEHNDSSLKELGLHPSANLHL 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
casp	NP_611080.1	UBA_FAF1	12..44	CDD:270596
		UBL	148..>182	CDD:176364
		UAS_FAF1	392..530	CDD:239288	20/143 (14%)
		Faf1_UBX	616..695	CDD:176366	21/83 (25%)
CG8892	NP_001260064.1	UBA_4	9..46	CDD:291236
		UAS	183..294	CDD:239256	20/143 (14%)
		UBQ	412..488	CDD:294102	19/75 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23322
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100