Protein Alignment casp and ubxn-3

DIOPT Version :10

• Sequence 1: NP_611080.1
• Gene: casp / 36769
• FlyBaseID: FBgn0034068
• Length: 695
• Species: Drosophila melanogaster
• Sequence 2: NP_001370738.1
• Gene: ubxn-3 / 173407
• WormBaseID: WBGene00018586
• Length: 613
• Species: Caenorhabditis elegans
• Alignment Length: 749
• Identity: 157/749 - (20%)
• Similarity: 281/749 - (37%)
• Gaps: 198/749 - (26%)

  Fly     1 MSENKDEALTSFQSITGIDDVGEAFSHLEAADWNLVEALSRVIPHEDAPLTSPHPILVPEPPA-- 63
            :.:::.|.|..:...|...|...|...|.:.:|||.:|:...:..||........||...|.|
 Worm     7 LEDDQREKLRQYTEFTHQQDYEVAIGTLASLNWNLEQAIEAHLMQEDKNDDEDPEILETIPAAAS 71

  Fly    64 -RNA-VESTNGFRPPGF----DEMPGTSNASGFFA------AALQNQNQNLNLNQPHIQQRFPTS 116
             ||| ..|::.|.|...    ||||.|.......|      ..:.||.:.|.::
 Worm    72 GRNAGASSSSRFEPEVINIEDDEMPATRGRRRGRAVTPDETTTVDNQVKRLRID----------- 125

  Fly   117 QLLAQLTSSINLDPASSQNNNQNVITFNIHFNQQLYQLRLPSEATVEQLKRKIFAETSVPVCRQA 181
                        |.:||.:|....     |..          .|.:.:.||           .||
 Worm   126 ------------DGSSSSSNGAAT-----HHR----------GAAIPRQKR-----------GQA 152

  Fly   182 IRGWP----PSKASDAQQLGTRLCNLDLSPENELILVDLTEDGFMDTEQDEVTQRVDKDFTIFIQ 242
            ....|    .|.||.:.:.|||
 Worm   153 TEPTPSSSGSSSASFSSRRGTR------------------------------------------- 174

  Fly   243 FESDPPLTLSLPGRMTVQEVKMNVFDIKSIPVRHQEWTGWPNGCDNDTTLAQSGIGLSHRFAVRS 307
              ::|                        :|..:||      ....::.....||     .|.|.
 Worm   175 --ANP------------------------VPPPNQE------PAHPESARQNGGI-----LASRH 202

  Fly   308 TERSAPTNSNQHN---------AFDVVTVDSESSTDE----FEDATD----FNNAEYIFTDSPPA 355
            ...:...|::.|:         ..||..|||:...|.    :||..|    .:::|.:...|
 Worm   203 NNHNNQQNNHHHHHQRIPINPRRVDVFNVDSDEDDDSMAIAYEDDDDGVHEVHHSEVVARGS--- 264

  Fly   356 QPPNRH--LIPNDTDDEISGSTQFVENYKARYGEP-C---------PEFFVGSLENA-KQLACLR 407
            .|||..  :||    |..|..:..:.|:.|.:.:. |         |.|:...|..| |:.....
 Worm   265 GPPNGRIPMIP----DGFSSVSDALRNFVAIFSDRFCSTPQTQAFMPPFYTEPLPAAVKEAFDHP 325

  Fly   408 SAKERKLLAIYLHHGKSILSNVFCDQLMKHESIIQTFKEKFVLYGWDMTYESNKDMFLSSLTACI 472
            :::.|:.|..|::|.:||.:|:|..|::..|::....:.::||:.||:|.:||..:||..|.|..
 Worm   326 NSEHRRPLLFYINHDRSIAANIFASQVLCSETVSTLIRHQYVLFPWDITSDSNLMLFLEYLQAAN 390

  Fly   473 SSNASLTARNI---KLDKLPAIMLVGKSRQLGSNCEVLSVIHGNIGLDDLLTRLIETCEMFEEQL 534
            ..:.....:.:   |::..|.:.:|.|.|   ::..::....|....|.::.:|:.....:.:..
 Worm   391 MGDVRTIIQRLAMSKIESFPLMAIVVKER---NSYRLVDYCRGTDTSDQVMEKLLSGVSEYSDIR 452

  Fly   535 QVEIRQEDERAARDQVKAEQDMAYQETLQADMAKDAAKRQKEAAQLAERKRMESERAEEDARRES 599
            ..|..:..||..|:.::.:|:..|:.:|.||.|:..||:|:...|..|.:|...|..||..||::
 Worm   453 MNEQSERREREEREAIRNQQEAEYKASLAADKARMEAKQQEIEEQRLEEERKLREEEEECVRRQT 517

  Fly   600 IRLVAQQSLPQEP--SEQETGTSKIRVRKPTGDFLERRFFINNNLQDLLNFVTANGFLIEEYKLI 662
            :    ..::|:||  |........::.|.|.|....|||....::|.|:|::::.|:..:::|..
 Worm   518 V----ASTVPEEPPASAPLAEIINVKFRLPEGGQDMRRFRRLESIQTLINYLSSKGYSPDKFKYF 578

  Fly   663 SS-WPRRDLTA-IESSQTLESLKLYPQETVILEE 694
            :| :|::::|. .:.|......|...:|.:.:||
 Worm   579 NSDFPKKEITRHFDLSHNFADTKWPAREQIFVEE 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
casp	NP_611080.1	UBA_FAF1	12..44	CDD:270596	8/31 (26%)
		Ubl1_FAF1	140..215	CDD:340649	13/78 (17%)
		Ubl2_FAF1	236..308	CDD:340650	8/71 (11%)
		UAS_FAF1	392..530	CDD:239288	33/141 (23%)
		tolA	<531..>600	CDD:236545	21/68 (31%)
		UBX_UBXN3A	616..695	CDD:340469	19/81 (23%)
ubxn-3	NP_001370738.1	UBA_4	12..53	CDD:464207	10/40 (25%)
		UAS	290..441	CDD:214737	35/153 (23%)
		UBX_UBXN3A	533..613	CDD:340469	19/80 (24%)