Protein Alignment casp and ubxn-3

DIOPT Version :9

• Sequence 1: NP_611080.1
• Gene: casp / 36769
• FlyBaseID: FBgn0034068
• Length: 695
• Species: Drosophila melanogaster
• Sequence 2: NP_001370738.1
• Gene: ubxn-3 / 173407
• WormBaseID: WBGene00018586
• Length: 613
• Species: Caenorhabditis elegans
• Alignment Length: 749
• Identity: 157/749 - (20%)
• Similarity: 281/749 - (37%)
• Gaps: 198/749 - (26%)

  Fly     1 MSENKDEALTSFQSITGIDDVGEAFSHLEAADWNLVEALSRVIPHEDAPLTSPHPILVPEPPA-- 63
            :.:::.|.|..:...|...|...|...|.:.:|||.:|:...:..||........||...|.|
 Worm     7 LEDDQREKLRQYTEFTHQQDYEVAIGTLASLNWNLEQAIEAHLMQEDKNDDEDPEILETIPAAAS 71

  Fly    64 -RNA-VESTNGFRPPGF----DEMPGTSNASGFFA------AALQNQNQNLNLNQPHIQQRFPTS 116
             ||| ..|::.|.|...    ||||.|.......|      ..:.||.:.|.::
 Worm    72 GRNAGASSSSRFEPEVINIEDDEMPATRGRRRGRAVTPDETTTVDNQVKRLRID----------- 125

  Fly   117 QLLAQLTSSINLDPASSQNNNQNVITFNIHFNQQLYQLRLPSEATVEQLKRKIFAETSVPVCRQA 181
                        |.:||.:|....     |..          .|.:.:.||           .||
 Worm   126 ------------DGSSSSSNGAAT-----HHR----------GAAIPRQKR-----------GQA 152

  Fly   182 IRGWP----PSKASDAQQLGTRLCNLDLSPENELILVDLTEDGFMDTEQDEVTQRVDKDFTIFIQ 242
            ....|    .|.||.:.:.|||
 Worm   153 TEPTPSSSGSSSASFSSRRGTR------------------------------------------- 174

  Fly   243 FESDPPLTLSLPGRMTVQEVKMNVFDIKSIPVRHQEWTGWPNGCDNDTTLAQSGIGLSHRFAVRS 307
              ::|                        :|..:||      ....::.....||     .|.|.
 Worm   175 --ANP------------------------VPPPNQE------PAHPESARQNGGI-----LASRH 202

  Fly   308 TERSAPTNSNQHN---------AFDVVTVDSESSTDE----FEDATD----FNNAEYIFTDSPPA 355
            ...:...|::.|:         ..||..|||:...|.    :||..|    .:::|.:...|
 Worm   203 NNHNNQQNNHHHHHQRIPINPRRVDVFNVDSDEDDDSMAIAYEDDDDGVHEVHHSEVVARGS--- 264

  Fly   356 QPPNRH--LIPNDTDDEISGSTQFVENYKARYGEP-C---------PEFFVGSLENA-KQLACLR 407
            .|||..  :||    |..|..:..:.|:.|.:.:. |         |.|:...|..| |:.....
 Worm   265 GPPNGRIPMIP----DGFSSVSDALRNFVAIFSDRFCSTPQTQAFMPPFYTEPLPAAVKEAFDHP 325

  Fly   408 SAKERKLLAIYLHHGKSILSNVFCDQLMKHESIIQTFKEKFVLYGWDMTYESNKDMFLSSLTACI 472
            :::.|:.|..|::|.:||.:|:|..|::..|::....:.::||:.||:|.:||..:||..|.|..
 Worm   326 NSEHRRPLLFYINHDRSIAANIFASQVLCSETVSTLIRHQYVLFPWDITSDSNLMLFLEYLQAAN 390

  Fly   473 SSNASLTARNI---KLDKLPAIMLVGKSRQLGSNCEVLSVIHGNIGLDDLLTRLIETCEMFEEQL 534
            ..:.....:.:   |::..|.:.:|.|.|   ::..::....|....|.::.:|:.....:.:..
 Worm   391 MGDVRTIIQRLAMSKIESFPLMAIVVKER---NSYRLVDYCRGTDTSDQVMEKLLSGVSEYSDIR 452

  Fly   535 QVEIRQEDERAARDQVKAEQDMAYQETLQADMAKDAAKRQKEAAQLAERKRMESERAEEDARRES 599
            ..|..:..||..|:.::.:|:..|:.:|.||.|:..||:|:...|..|.:|...|..||..||::
 Worm   453 MNEQSERREREEREAIRNQQEAEYKASLAADKARMEAKQQEIEEQRLEEERKLREEEEECVRRQT 517

  Fly   600 IRLVAQQSLPQEP--SEQETGTSKIRVRKPTGDFLERRFFINNNLQDLLNFVTANGFLIEEYKLI 662
            :    ..::|:||  |........::.|.|.|....|||....::|.|:|::::.|:..:::|..
 Worm   518 V----ASTVPEEPPASAPLAEIINVKFRLPEGGQDMRRFRRLESIQTLINYLSSKGYSPDKFKYF 578

  Fly   663 SS-WPRRDLTA-IESSQTLESLKLYPQETVILEE 694
            :| :|::::|. .:.|......|...:|.:.:||
 Worm   579 NSDFPKKEITRHFDLSHNFADTKWPAREQIFVEE 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
casp	NP_611080.1	UBA_FAF1	12..44	CDD:270596	8/31 (26%)
		UBL	148..>182	CDD:176364	4/33 (12%)
		UAS_FAF1	392..530	CDD:239288	33/141 (23%)
		Faf1_UBX	616..695	CDD:176366	19/81 (23%)
ubxn-3	NP_001370738.1	UBA_4	13..53	CDD:405274	10/39 (26%)
		UAS	290..441	CDD:214737	35/153 (23%)
		UBX_UBXN3A	533..613	CDD:340469	19/80 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166126
Domainoid	1	1.000	96	1.000	Domainoid score	I4609
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	149	1.000	Inparanoid score	I2978
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D363568at33208
OrthoFinder	1	1.000	-	-		FOG0006030
OrthoInspector	1	1.000	-	-		otm14391
orthoMCL	1	0.900	-	-		OOG6_107273
Panther	1	1.100	-	-	LDO	PTHR23322
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2328
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.930