DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment casp and Ubxn8

DIOPT Version :9

Sequence 1:	NP_611080.1	Gene:	casp / 36769	FlyBaseID:	FBgn0034068	Length:	695	Species:	Drosophila melanogaster
Sequence 2:	NP_848763.2	Gene:	Ubxn8 / 108159	MGIID:	1337129	Length:	277	Species:	Mus musculus

Alignment Length:	190	Identity:	50/190 - (26%)
Similarity:	89/190 - (46%)	Gaps:	28/190 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   521 TRLIETCEMFEEQLQVEIRQEDER------------AARDQVKAEQDMAYQETLQADMAK---DA 570
            :|.||  .:.:.|.::::::.:||            |....::.::|..::.:.||....   :|
Mouse    96 SRYIE--NVLKPQQEMKLKKLEERFYQMTGETWKLTAGHRLLEGDEDSEFENSSQASFETINGEA 158

  Fly   571 AKRQKEAAQLAERKRMESERAEEDARRESIRLVAQQSLPQEPSEQETGTSKIRVRKPTGDFLERR 635
            |:||    .|.:.....|..|....|:|      ...||:||||.......:.:|.|.|..|.||
Mouse   159 ARRQ----NLPKFSTEISPAARPLLRKE------VPDLPEEPSETAEEVVTVALRCPNGRVLRRR 213

  Fly   636 FFINNNLQDLLNFVTANGFLIEEYKLISSWPRRDLTAIESSQTLESLKLYPQETVILEER 695
            ||.:.|.|.||:::...|:....|:|.:|:|||.| .:|...:||.:.:.....:.:||:
Mouse   214 FFKSWNSQVLLDWMMKVGYHKSLYRLSNSFPRRAL-EVEGGSSLEDIGITVDTVLNVEEK 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
casp	NP_611080.1	UBA_FAF1	12..44	CDD:270596
		UBL	148..>182	CDD:176364
		UAS_FAF1	392..530	CDD:239288	3/8 (38%)
		Faf1_UBX	616..695	CDD:176366	24/78 (31%)
Ubxn8	NP_848763.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	64..89
Ubxn8	NP_848763.2	UBQ	192..271	CDD:294102	24/79 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1363
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810