DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8399 and AT5G54830

DIOPT Version :9

Sequence 1:	NP_001286472.1	Gene:	CG8399 / 36768	FlyBaseID:	FBgn0034067	Length:	656	Species:	Drosophila melanogaster
Sequence 2:	NP_200294.1	Gene:	AT5G54830 / 835573	AraportID:	AT5G54830	Length:	907	Species:	Arabidopsis thaliana

Alignment Length:	716	Identity:	136/716 - (18%)
Similarity:	237/716 - (33%)	Gaps:	198/716 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 SLPQGAPETVC-DTMLPFHSGGSVLPQNSVSPFSVETSSSTLGQGQTLRVDLTGVPAGLSFGGY- 92
            |:.:|....|| ||:  :....||       ..||..:....|.    |:|      |:||..|
plant   257 SVKEGTATGVCPDTV--YEEADSV-------GSSVNNTKLVYGH----RID------GVSFVRYR 302

  Fly    93 --MIQARNR--------------------NPPHQIIGQFGPARDGTIKLMNCENSVNNSATHSN- 134
              :..:.|:                    .||..|...:.|...|.::..|..:...|.:.|.:
plant   303 RPLNDSDNKFDFPVNSTESLTVIWALGVIKPPDVINPYYLPVNHGGVESENFGHFSLNLSDHVDE 367

  Fly   135 -AGP-------KQQVILEWQSPVDFLGQVVFNATIAQSYNEFWVGVPSQPVQIVRRDLSAAPPLP 191
             .||       .|.||:     .|....:|..|..:..|..     |..|.:::..:...||.|.
plant   368 CLGPLDADNKYDQDVII-----ADAHAPLVVTAGPSVHYPN-----PPNPSKVLYINKKEAPVLK 422

  Fly   192 TQSP-----SAPAGTTRAPYVPPSYVAPNNVVAVSSDPIYNGCGQSKNCFGFP------------ 239
            .:..     |..||...:.|:...::..|..:...::.||.|..::......|
plant   423 VERGVPVKFSIEAGHDVSFYITSDFLGGNASLRNRTETIYAGGQETHGVLSSPSELVWAPNRNTP 487

  Fly   240 --------------------DGCVATKSCTSITV--------VTVRGDVFEFEIQSGKGTNAAYV 276
                                ||.::.....|:.:        .|:.||......:..|  .:.|:
plant   488 DQLYYHSIFQEKMGWKVQVVDGGLSDMYNNSVNLDDQQVKFFWTIVGDSISIAARGEK--KSGYL 550

  Fly   277 AVGLSDDAKMGDDLTTECV-------PENGRVNLY----SSLTSASPYSAVRSNVNQNSARLLDA 330
            |:|      .|.::|....       ...|.||.|    .|.::..|.:...:.|...|.
plant   551 AIG------FGSEMTNSYAYIGWFDRNGTGHVNTYWIDGESASAVHPTTENMTYVRCKSE----- 604

  Fly   331 SIVDGVIYCRV-----------QRDAVTNVQGRTFDLRNGKYHLLVASGSSLKENSVGYHDIGRL 384
               :|:|....           .|....|:...|..|:     ::.|.|:...:..:...::..:
plant   605 ---EGIITLEFTRPLKPSCSHRDRPECKNMIDPTTPLK-----VIWAMGAKWTDGQLTERNMHSV 661

  Fly   385 PSAQPINL------AEV-QDLSGSSRLLIQLHGAFMIAAWIGTTSLGIIFARYFKQTWVGSQSCG 442
            .|.:|:.:      ||. |||    |.::.:||..|..||......||:.|||.|.       ..
plant   662 TSQRPVRVMLTRGSAEADQDL----RPVLGVHGFMMFLAWGILLPGGILSARYLKH-------IK 715

  Fly   443 TDQWFAWHRLLMVTTWSLTVAAYVLIWVELKQAVWHA-HSIIGLITVILCFIQPIGALFRPGPN- 505
            .|.||..|..|..:..::.....:....||....:.: |...|...::|...||:.|..||...
plant   716 GDGWFKIHMYLQCSGLAIVFLGLLFAVAELNGFSFSSTHVKFGFTAIVLACAQPVNAWLRPAKPA 780

  Fly   506 -----DKKRPYFNWGHWLGGNLAHILGIVTIFFSVK-LPKAELPEWMD--------WILVSFVVV 556
                 ..||..:.:.|.:.|..|.::|:|.:|..:| |.:....|.:|        |:   |:.|
plant   781 QGELISSKRLIWEYSHSIVGQSAVVVGVVALFTGMKHLGERNGTENVDGLNLALGLWV---FLCV 842

  Fly   557 HVLVHLIF-------SIGLCLNHWQIGGMASERHLSQRANTFQMGDMSHHQQHAMRNGMSMERKM 614
            ..:.:|.:       :..|...:|.:|.:..:..:....:.....|.....    |||..||.::
plant   843 VTVAYLEYRERGRRRARNLSRGNWVLGNVEEDDSIDLIDSRGGFRDKDDED----RNGGRMEIQL 903

  Fly   615 D 615
            :
plant   904 E 904

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8399	NP_001286472.1	Reeler	40..170	CDD:280232	32/162 (20%)
		DOMON_SDR_2_like	223..392	CDD:187686	34/230 (15%)
		Cyt_b561_FRRS1_like	358..553	CDD:176490	49/217 (23%)
AT5G54830	NP_200294.1	DM13	42..145	CDD:128929
		DoH	183..358	CDD:214768	24/119 (20%)
		DoH	523..674	CDD:214768	27/171 (16%)
		Cyt_b561_FRRS1_like	682..850	CDD:176490	44/181 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4293
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D599276at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820