DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8399 and M03A1.8

DIOPT Version :9

Sequence 1:	NP_001286472.1	Gene:	CG8399 / 36768	FlyBaseID:	FBgn0034067	Length:	656	Species:	Drosophila melanogaster
Sequence 2:	NP_001122624.1	Gene:	M03A1.8 / 6418630	WormBaseID:	WBGene00077490	Length:	382	Species:	Caenorhabditis elegans

Alignment Length:	393	Identity:	91/393 - (23%)
Similarity:	155/393 - (39%)	Gaps:	84/393 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   289 DLTTECVPENGRVNLYSSLTSASPYSAVRSNVNQNSARLLD--------ASIVDGVIYCRVQRDA 345
            ::|..|...:|.::|  ...:....|||:.   .|...||:        :|.:|...| :::...
Worm    34 NITVTCNKNDGFMSL--KWKTEEKRSAVKI---YNGVNLLEFVCGFPIGSSNIDVKTY-KLETLK 92

  Fly   346 VTNVQGRTFDLRNGKYHLLVASGSSLK---ENS--VGYHDIGRLPSAQPINLAEVQDLSGS-SRL 404
            ..|:.....|...|.. ||::..||||   |.|  ..:|:|     ..|    :::.||.. .||
Worm    93 SENLTSCEIDFYPGDV-LLMSESSSLKWSNEKSEFFNFHEI-----CNP----KIEGLSKEFKRL 147

  Fly   405 LIQLHGAFMIAAWIGTTSLGIIFARYFKQTWVGSQSCGTDQWFAWHR----------------LL 453
            |::||...||..|:.....|.:||||.:|.:......|...||..||                :|
Worm   148 LVKLHAILMILGWLFFVPTGFLFARYGRQVFKNHTIYGMFVWFQIHRASTFIGVCCIVTSILCIL 212

  Fly   454 MVTTWSLTVAAYVLIWVELKQAVWH---AHSIIGLITVILCFIQPIGALFRPGPNDKKRPYFNWG 515
            :.|.|:         |.......|:   .|:..|.|:.||.|.||:.:|.|..|::.:|..|||.
Worm   213 ISTNWT---------WKGTGSEAWYWTQWHTDFGTISTILAFSQPLNSLLRCPPSNSQRSIFNWA 268

  Fly   516 HWLGGNLAHILGIVTIFF-SVKLPKAELPEWMDWILVSFVVVHVLVHLIFSIGLCLNHWQIGGMA 579
            |.:.|.|::...:..|:. :....|......|:.:|.|...:     |..:.|..:.:.:
Worm   269 HRIVGLLSYTFAVAAIYVAAANYRKTWSEPTMEIVLTSVPTI-----LCIATGFVVLYLE----- 323

  Fly   580 SERHLSQRANTFQMGDMSHHQQHAMRNGMSMERKMDAPYAGMRKGLLGVYGVVLILFVTVLILLV 644
                 |::.|.::..:|....:   :|....||......:.|       :.||.|.|...:.|.:
Worm   324 -----SEQRNGYREVEMIEKSE---KNSKKPERLQLIQISWM-------FAVVGICFGVAISLSL 373

  Fly   645 VLA 647
            ::|
Worm   374 LIA 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8399	NP_001286472.1	Reeler	40..170	CDD:280232
		DOMON_SDR_2_like	223..392	CDD:187686	27/115 (23%)
		Cyt_b561_FRRS1_like	358..553	CDD:176490	60/220 (27%)
M03A1.8	NP_001122624.1	B561	151..279	CDD:214769	39/136 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156354
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4293
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D464310at33208
OrthoFinder	1	1.000	-	-		FOG0001198
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.750