DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8399 and l(2)34Fc

DIOPT Version :9

Sequence 1:	NP_001286472.1	Gene:	CG8399 / 36768	FlyBaseID:	FBgn0034067	Length:	656	Species:	Drosophila melanogaster
Sequence 2:	NP_001285930.1	Gene:	l(2)34Fc / 34838	FlyBaseID:	FBgn0261534	Length:	159	Species:	Drosophila melanogaster

Alignment Length:	169	Identity:	45/169 - (26%)
Similarity:	83/169 - (49%)	Gaps:	19/169 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LVTALLAVAIWPDPGQSLPQGAPETVCDTMLPFHSGGSVLPQNSVSPFSVETSSSTLGQGQTLRV 78
            ::.|.||:::     .:...|||:..|..:.|.|  |:.| |.:..|:|: :..|.:...|.|.:
  Fly     6 VLAACLAISV-----HAYSDGAPKAACRDLTPQH--GAKL-QVTKPPYSI-SGPSHVRSDQKLTL 61

  Fly    79 DLTGVPAGLSFGGYMIQARNRNPPHQIIGQFGPARDGTIKLMNCENSVNNSATHSNA---GPKQQ 140
            .|    .|..|.|:|||||:..  ::::|||........:.::|... :::.||.:|   .|...
  Fly    62 TL----GGDEFLGFMIQARDGQ--NRVVGQFQVVDSVHSQTLDCSGK-DDTITHLSAQKGKPLTG 119

  Fly   141 VILEWQSPVDFLGQVVFNATIAQSYNEFWVGVPSQPVQI 179
            :..:|..|..:.|.|.|.||:.|:...:|||..::.:.:
  Fly   120 ITFDWIPPAGYKGNVKFMATVVQTGFVYWVGRVTKDIDV 158

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8399	NP_001286472.1	Reeler	40..170	CDD:280232	36/132 (27%)
		DOMON_SDR_2_like	223..392	CDD:187686
		Cyt_b561_FRRS1_like	358..553	CDD:176490
l(2)34Fc	NP_001285930.1	Reeler	27..149	CDD:280232	36/132 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446185
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7160
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001198
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45828
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3670
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.920