Protein Alignment CG8399 and Frrs1

DIOPT Version :9

• Sequence 1: NP_001286472.1
• Gene: CG8399 / 36768
• FlyBaseID: FBgn0034067
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: XP_038959758.1
• Gene: Frrs1 / 310810
• RGDID: 1306883
• Length: 592
• Species: Rattus norvegicus
• Alignment Length: 591
• Identity: 171/591 - (28%)
• Similarity: 267/591 - (45%)
• Gaps: 100/591 - (16%)

  Fly    11 LATLVTALLAVAIWPDPGQSLPQGAPETVCDTMLPFHSGGSVLPQNSVSPFSVETSSSTLGQ--- 72
            |:.||.|||..::     .:.|.|.....|         ..::||::.||.|......|:.|
  Rat     8 LSVLVCALLICSV-----TAYPNGRVARSC---------AGMIPQHNHSPQSDPVHKITVSQMKF 58

  Fly    73 --GQTLRVDLTGVPAGLSFGGYMIQARN----RNPPHQIIGQFGPARDGTIKLMNCENSVNNSAT 131
              |..::|.|:|.|    |.|::::|||    ..||   ||.|......:.:::.||:....:.:
  Rat    59 KPGDQIKVTLSGPP----FRGFLLEARNAEDLSGPP---IGTFTLIDSDSSQILTCEDVQGFAVS 116

  Fly   132 HSNAGPKQQVILEWQSPVDFLGQVVFNATIAQSYNEFWVGVP----SQPVQIVRRDLSAAPPLPT 192
            |:::..|.::.:.|.:|......|.|.||:.|.|..:||.:|    |||         :|||..|
  Rat   117 HTSSSIKTEIKVYWNAPSSAPDHVQFLATVVQKYKIYWVKIPGPVISQP---------SAPPFTT 172

  Fly   193 QSPSAPAGTTRAPYVPPSYVAPNNVVAVSSDPI-YNGCGQSKNCFGFPDGCVATK--SCTSITVV 254
                 |..||:     |..:||:  |:..:.|. .:.||..|.|...|..|....  :|..::
  Rat   173 -----PEATTQ-----PLTMAPS--VSHLTKPFSASECGNKKFCVRSPLNCDPENEPACVFLS-- 223

  Fly   255 TVRGDVFEFEIQS----GKGTNAAYVAVGLSDDAKMGDDLTTECVPENGRVNLYSSLTSASPYSA 315
                  |..|.||    ..|.:..||:...|.|..||||....|:.|:..|.:..|..:...|..
  Rat   224 ------FTRENQSVMVEMSGPSDGYVSFAFSHDQWMGDDDAYLCIYEDQTVYIQPSYLTGRSYPV 282

  Fly   316 V--RSNVNQNSARLLDASIVDGVIYCRVQRDAVTNVQGRTFDLRNGKYHLLVASGSSLKENSVGY 378
            :  |..:...:.||     .||||.|..:|: :|..:.:...:.|..|::..|.|::
  Rat   283 MDSRGTLEDMAWRL-----ADGVIQCSFRRN-ITLPEAKNRFVLNESYYIFYAEGAA-------- 333

  Fly   379 HDIGRL--PSAQPINLAEVQDLSGS--------SRLLIQLHGAFMIAAWIGTTSLGIIFARYFKQ 433
            || ||:  .|.||:...|..:::|:        |..|::.|||.|..||:.|.|.|::.||:|:.
  Rat   334 HD-GRIFRHSQQPLITYEKYNVTGTPQNVGGSRSSALLKAHGALMFVAWVTTVSTGVLVARFFRS 397

  Fly   434 TWVGSQSCGTDQWFAWHRLLMVTTWSLTVAAYVLIWVELKQAVWHA--HSIIGLITVILCFIQPI 496
            .|..:...|...||..||:||:.|..||..|:||.:|......|.|  |..:|.|.:.|..:||:
  Rat   398 VWSKAFFFGQAAWFQVHRMLMLATSMLTCVAFVLPFVYRAGWSWRAGYHPYLGCIVMTLAVLQPL 462

  Fly   497 GALFRPGPNDKKRPYFNWGHWLGGNLAHILGIVTIFFSVKLPKAELPE-WMDWILVSFVVVHVLV 560
            .|.|||..:|.:|..|||.||..|..|.|:.:..:|..:.||..:||. ...:.::.|||.|:..
  Rat   463 LATFRPPLHDPRRQVFNWTHWSVGTAARIIAVAAMFLGMDLPGLDLPSPQKTYAMMGFVVWHIGT 527

  Fly   561 HLIFSI 566
            .:|..|
  Rat   528 EVILEI 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8399	NP_001286472.1	Reeler	40..170	CDD:280232	35/138 (25%)
		DOMON_SDR_2_like	223..392	CDD:187686	47/179 (26%)
		Cyt_b561_FRRS1_like	358..553	CDD:176490	69/207 (33%)
Frrs1	XP_038959758.1	Reeler	32..155	CDD:396550	35/138 (25%)
		DOMON_SDR_2_like	192..354	CDD:187686	48/184 (26%)
		Cyt_b561_FRRS1_like	320..533	CDD:176490	74/221 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335030
Domainoid	1	1.000	97	1.000	Domainoid score	I7102
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H40653
Inparanoid	1	1.050	180	1.000	Inparanoid score	I3902
OMA	1	1.010	-	-		QHG46024
OrthoDB	1	1.010	-	-		D464310at33208
OrthoFinder	1	1.000	-	-		FOG0001198
OrthoInspector	1	1.000	-	-		oto95494
orthoMCL	1	0.900	-	-		OOG6_102865
Panther	1	1.100	-	-	O	PTHR45828
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4013
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.910