DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8399 and Frrs1l

DIOPT Version :9

Sequence 1:	NP_001286472.1	Gene:	CG8399 / 36768	FlyBaseID:	FBgn0034067	Length:	656	Species:	Drosophila melanogaster
Sequence 2:	NP_001136437.1	Gene:	Frrs1l / 230235	MGIID:	2442704	Length:	293	Species:	Mus musculus

Alignment Length:	231	Identity:	60/231 - (25%)
Similarity:	98/231 - (42%)	Gaps:	28/231 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 RRDLSAAPPLPTQSPSAPAGTTRAPYVPPSYVAPNNVVAVSSDPI-------YNGCGQSKNCF-- 236
            |.|..|...:|....|  .||..:.:....|::.......::.|:       ...||::|.||
Mouse    47 RGDAGADEAVPRHDSS--YGTFASEFYDLRYLSEEGYPFPTAPPVDPFAKIKVEDCGRTKGCFRY 109

  Fly   237 GFPDGCVATKSCTSITVVTVRGDVFEFEIQSGKGTNAAYVAVGLSDDAKMGDDLTTECV-PENGR 300
            |.| ||.| ::|.......:.|...|||:.:   ....:||||.|.|.|||.|....|| .:|||
Mouse   110 GKP-GCNA-ETCDYFLSYRMIGADVEFELSA---DTDGWVAVGFSSDKKMGGDDVMACVHDDNGR 169

  Fly   301 VNLYSSLTSASPYSAVR--SNVNQNSARLLDASIVDGVIYCRVQRDAVTNVQGRTFDLRNGKYHL 363
            |.:...      |:..:  ..|.:|.||..:....:..:.||.:|...........||....|:|
Mouse   170 VRIQHF------YNVGQWAKEVQRNPARDEEGVFENNRVTCRFKRPVNVPRDETIVDLHLSWYYL 228

  Fly   364 LVASGSSLKENSVGYHDIGRLP-SAQPINLAEVQDL 398
            . |.|.:: :.::..|||...| |.:.:::.:.:|:
Mouse   229 F-AWGPAI-QGAITRHDIDSPPASERVVSIYKYEDI 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8399	NP_001286472.1	Reeler	40..170	CDD:280232
		DOMON_SDR_2_like	223..392	CDD:187686	51/181 (28%)
		Cyt_b561_FRRS1_like	358..553	CDD:176490	10/42 (24%)
Frrs1l	NP_001136437.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	29..60		4/12 (33%)
Frrs1l	NP_001136437.1	DOMON_SDR_2_like	94..253	CDD:187686	50/171 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831295
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4293
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.700