DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8399 and C44B7.5

DIOPT Version :9

Sequence 1:	NP_001286472.1	Gene:	CG8399 / 36768	FlyBaseID:	FBgn0034067	Length:	656	Species:	Drosophila melanogaster
Sequence 2:	NP_495404.1	Gene:	C44B7.5 / 174124	WormBaseID:	WBGene00016627	Length:	236	Species:	Caenorhabditis elegans

Alignment Length:	187	Identity:	48/187 - (25%)
Similarity:	79/187 - (42%)	Gaps:	29/187 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   233 KNCFGFPDGCVATKSCTSITVVTVRGDVFEFEIQSGKGTNAAYVAVGLSDDAKMGDDLTTECVPE 297
            |.|.|.|.|||.|:...:.:.:: .|...|.||......:..::|:|.|.|.||.||....|:.:
Worm    36 KYCVGLPRGCVGTECNFAFSSIS-NGTHTEIEIFGNSVIDKTWLAIGYSADKKMEDDFVVFCIRD 99

  Fly   298 NGRVNLYS-SLTSASPYSAVRSN----------VNQNSARLLDASIV-----DGVIYCRVQRDAV 346
            :...|:.. ...:...|:...||          .|:|....||..:.     :..:||::.. .|
Worm   100 DAGTNMNKLDQMAGLAYNGKHSNEMTGTIENIKKNKNDKFGLDLEMKEYEKDEQTLYCKMAH-RV 163

  Fly   347 TNVQGRTFDLRNGKYHLLVASGSSLKENSVGYHDIGRLPSAQPINLAEVQDLSGSSR 403
            ..:..| |::  .|..:|:|.|:.:| ..:.||...|       |...:.||||.|:
Worm   164 EPIIDR-FNV--SKVEILMAKGTWMK-GGLSYHGNTR-------NNTGIIDLSGESK 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8399	NP_001286472.1	Reeler	40..170	CDD:280232
		DOMON_SDR_2_like	223..392	CDD:187686	42/174 (24%)
		Cyt_b561_FRRS1_like	358..553	CDD:176490	14/46 (30%)
C44B7.5	NP_495404.1	DOMON_SDR_2_like	26..200	CDD:187686	43/176 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156351
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4293
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830