DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8399 and M03A1.3

DIOPT Version :9

Sequence 1:	NP_001286472.1	Gene:	CG8399 / 36768	FlyBaseID:	FBgn0034067	Length:	656	Species:	Drosophila melanogaster
Sequence 2:	NP_494805.3	Gene:	M03A1.3 / 173791	WormBaseID:	WBGene00019746	Length:	352	Species:	Caenorhabditis elegans

Alignment Length:	294	Identity:	67/294 - (22%)
Similarity:	103/294 - (35%)	Gaps:	83/294 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   338 YCRVQRDAVTNVQGRTFDLRN----------GKYHLLVASGSSLKENSVGYHDIGRLPSAQ---- 388
            :|....::......||.|..|          .|.|:|...|..:..:.....:.|:...||
Worm    26 FCYSPNESTKVTLTRTGDSLNLRIYDENSAIRKVHILQKEGKDVLVDCTNKKEDGKTCEAQLTVD 90

  Fly   389 ------PINLAEVQDLSGSS--------------------RLLIQLHGAFMIAAWIGTTSLGIIF 427
                  ||:: ::.|...|.                    |...:.|...||..|:.....|.:|
Worm    91 QFEKNLPISI-KLSDSQTSDPISLEALVPPAQEGLTKQQRRQFSKAHAILMIFGWLLFVPSGFLF 154

  Fly   428 ARYFKQTWVGSQSCGTDQWFAWHR-------LLMVT-----------TWSLTVAA--YVLIWVEL 472
            ||..|..:......|:..||..||       :.|.|           ||..|.:.  |   |.|:
Worm   155 ARLGKDLFKEQTLFGSAVWFQIHRAANFMGVVCMCTSMLCIFISTQWTWKGTGSGSKY---WTEV 216

  Fly   473 KQAVWHAHSIIGLITVILCFIQPIGALFRPGPNDKKRPYFNWGHWLGGNLAHILGIVTIFF-SVK 536
                   |:.:|:|:.:|...|||.:|||.||...:|..|||.|...|.:|:.|.:..|.. :|:
Worm   217 -------HTDLGVISTVLAVAQPINSLFRCGPTHSQRIIFNWAHRCVGIVAYTLALTAIIIAAVQ 274

  Fly   537 LPKAELPEWMDWILVSFVVVHVLVHLIFSIGLCL 570
            ..:......|:.:||           ...|.:||
Worm   275 FKRIWNEPLMELVLV-----------CLPIAICL 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8399	NP_001286472.1	Reeler	40..170	CDD:280232
		DOMON_SDR_2_like	223..392	CDD:187686	14/73 (19%)
		Cyt_b561_FRRS1_like	358..553	CDD:176490	60/255 (24%)
M03A1.3	NP_494805.3	Cyt_b561_FRRS1_like	99..305	CDD:176490	53/221 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156357
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4293
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7160
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D464310at33208
OrthoFinder	1	1.000	-	-		FOG0001198
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.700