DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8399 and reeld1

DIOPT Version :9

Sequence 1:	NP_001286472.1	Gene:	CG8399 / 36768	FlyBaseID:	FBgn0034067	Length:	656	Species:	Drosophila melanogaster
Sequence 2:	XP_031751366.1	Gene:	reeld1 / 100485235	-ID:	-	Length:	524	Species:	Xenopus tropicalis

Alignment Length:	277	Identity:	63/277 - (22%)
Similarity:	104/277 - (37%)	Gaps:	74/277 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 MRSWLATLVTALLAVAI------WPDPGQSLPQGAPETVCDTMLPFHSGGSVLPQNSVSPF-SVE 64
            |.||:...:.|.|.:.:      ......:...||..:.|..|.|.|....  |||....: ::.
Frog    23 MFSWVEDRIKAQLCLGLACASVCLISYSAAFSHGASLSACSDMRPKHIRAQ--PQNPKKNYIAIR 85

  Fly    65 TSSSTLGQGQTLRVDLTGVPAGLSFGGYMIQARNRNPPHQIIGQFGPARDGTIKLMNCENSVNNS 129
            |:.::...|.|:.|.   :.:...|.|:::||| |....|:.|.|.....|. ||::|... .::
Frog    86 TNRTSYLPGDTVPVT---IRSSRDFMGFLLQAR-RISNDQVAGSFVFIPPGA-KLLHCFED-GDT 144

  Fly   130 ATHSNAGPKQQVILEWQSPVDFLGQVVFNATIAQSYNEFW---------------------VG-- 171
            .|||:...|:.:...|:||...:|.:.|..::.|||..:|                     ||
Frog   145 VTHSDKSLKRNLSFVWKSPDQPVGDIRFFLSVVQSYFVYWSRIESAIVSSKILNNTHASSHVGTS 209

  Fly   172 --VPS-------QPVQ-------------------IVRRDLSAAPPLPTQS------PSAPAGTT 202
              ||:       :|.|                   |....:|.|...|:.:      |....|||
Frog   210 KTVPTADSAQSWKPEQSSVYLLSVSGLTNVTAANTIALTSVSTAGTKPSTNASKSYKPMMSVGTT 274

  Fly   203 RAPYVPPSYVAPNNVVA 219
            ..|.||.  :..:|::|
Frog   275 PKPVVPS--LNKSNIIA 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8399	NP_001286472.1	Reeler	40..170	CDD:280232	37/151 (25%)
		DOMON_SDR_2_like	223..392	CDD:187686
		Cyt_b561_FRRS1_like	358..553	CDD:176490
reeld1	XP_031751366.1	Reeler	62..184	CDD:396550	36/129 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45828
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010