DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment EMC7 and emc7

DIOPT Version :9

Sequence 1:	NP_611078.1	Gene:	EMC7 / 36767	FlyBaseID:	FBgn0034066	Length:	245	Species:	Drosophila melanogaster
Sequence 2:	NP_001072567.1	Gene:	emc7 / 780022	XenbaseID:	XB-GENE-945123	Length:	237	Species:	Xenopus tropicalis

Alignment Length:	247	Identity:	86/247 - (34%)
Similarity:	133/247 - (53%)	Gaps:	43/247 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 ALLALVSCEVII-----GQDELVDEVSGLYTIEGR-----VSPPDSIFSPTQGGGRSAPVNKNTP 64
            |||.|.|.::.:     |.|:        :.:|||     |.|.|
Frog    21 ALLQLCSADLDVLSPGSGSDK--------FKVEGRAVVPGVRPQD-------------------- 57

  Fly    65 KWHTEITLSINDGEFKGFVREDGQFMISGVPSGSYILDVHHPDVFYEPVRVEINPKGKFRARKVN 129
             |.....:.::..|..||:|.||.|::..||||||:::|..|...:|||||:|..|||.|||.||
Frog    58 -WVNTARVLVDGEEHVGFLRTDGSFVVHDVPSGSYVVEVISPAHRFEPVRVDITSKGKMRARYVN 121

  Fly   130 FVQPAQIMQVAYPLRVKPLMPFKYFQTREQWKITDFLFSPMVLMMVLPLLLMLVLPKMIN--DPE 192
            .::.::::::.|||::|...|..||..||.|..||||.:|||:|||||||:.::|||::|  |||
Frog   122 HIKTSEVVRLPYPLQMKSSGPPSYFIKRETWGWTDFLMNPMVMMMVLPLLIFVLLPKVVNTSDPE 186

  Fly   193 TKKEID-NLQFPKMGNDMPEISEMLTSLLTGKQPEPKEKKPAPAVRQAKKRK 243
            .::|:: ::.......::|::||.:|.|.|.|. ..|......|.:...||:
Frog   187 MRREMEQSMNMLNTNPELPDVSEFMTRLFTSKS-SSKSSGSGKAGKSVGKRR 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EMC7	NP_611078.1	DUF2012	68..168	CDD:286513	43/99 (43%)
emc7	NP_001072567.1	DUF2012	55..165	CDD:312808	49/130 (38%)
emc7	NP_001072567.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	216..237		5/21 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I6761
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10597
Inparanoid	1	1.050	144	1.000	Inparanoid score	I4345
OMA	1	1.010	-	-		QHG51947
OrthoDB	1	1.010	-	-		D1348328at2759
OrthoFinder	1	1.000	-	-		FOG0003435
OrthoInspector	1	1.000	-	-		otm47584
Panther	1	1.100	-	-	LDO	PTHR13605
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2915
SonicParanoid	1	1.000	-	-		X3893
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110