DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment EMC7 and Emc7

DIOPT Version :9

Sequence 1:	NP_611078.1	Gene:	EMC7 / 36767	FlyBaseID:	FBgn0034066	Length:	245	Species:	Drosophila melanogaster
Sequence 2:	NP_598510.1	Gene:	Emc7 / 73024	MGIID:	1920274	Length:	241	Species:	Mus musculus

Alignment Length:	239	Identity:	80/239 - (33%)
Similarity:	130/239 - (54%)	Gaps:	50/239 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FTALLALVSCEVIIGQDELVDEVSGL---------------YTIEGR-----VSPPDSIFSPTQG 52
            |:.||.|:|      .|....||.|.               :.||||     |.|.|
Mouse     9 FSVLLLLLS------GDAHSSEVPGAAAEGPGGSGVGLGDRFKIEGRAVVPGVKPQD-------- 59

  Fly    53 GGRSAPVNKNTPKWHTEITLSINDGEFKGFVREDGQFMISGVPSGSYILDVHHPDVFYEPVRVEI 117
                         |.:...:.::..|..||::.||.|::..:|||||:::|..|...::||||:|
Mouse    60 -------------WISAARVLVDGEEHVGFLKTDGSFVVHDIPSGSYVVEVISPAYKFDPVRVDI 111

  Fly   118 NPKGKFRARKVNFVQPAQIMQVAYPLRVKPLMPFKYFQTREQWKITDFLFSPMVLMMVLPLLLML 182
            ..|||.|||.||:::.::::::.|||::|...|..||..||.|..||||.:|||:|||||||:.:
Mouse   112 TSKGKMRARYVNYIKTSEVVRLPYPLQMKSSGPPSYFIKRESWGWTDFLMNPMVMMMVLPLLIFV 176

  Fly   183 VLPKMIN--DPETKKEID-NLQFPKMGNDMPEISEMLTSLLTGK 223
            :|||::|  ||:.::|:: ::......:::|::||.:|.|.:.|
Mouse   177 LLPKVVNTSDPDMRREMEQSMNMLNSNHELPDVSEFMTRLFSSK 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EMC7	NP_611078.1	DUF2012	68..168	CDD:286513	40/99 (40%)
Emc7	NP_598510.1	DUF2012	56..167	CDD:286513	46/131 (35%)
Emc7	NP_598510.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	216..241		2/5 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847607
Domainoid	1	1.000	102	1.000	Domainoid score	I6867
eggNOG	1	0.900	-	-		E1_KOG3306
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10597
Inparanoid	1	1.050	142	1.000	Inparanoid score	I4458
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51947
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003435
OrthoInspector	1	1.000	-	-		oto92120
orthoMCL	1	0.900	-	-		OOG6_102814
Panther	1	1.100	-	-	LDO	PTHR13605
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2915
SonicParanoid	1	1.000	-	-		X3893
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790