DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment EMC7 and C35D10.1

DIOPT Version :9

Sequence 1:	NP_611078.1	Gene:	EMC7 / 36767	FlyBaseID:	FBgn0034066	Length:	245	Species:	Drosophila melanogaster
Sequence 2:	NP_001033353.1	Gene:	C35D10.1 / 175651	WormBaseID:	WBGene00016439	Length:	222	Species:	Caenorhabditis elegans

Alignment Length:	224	Identity:	91/224 - (40%)
Similarity:	140/224 - (62%)	Gaps:	21/224 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 ALLALVSCEVIIGQDELV---DEVSGLYTIEGRVSPPDSIFSPTQGGGRSAPVNKNTPKWHTEIT 71
            ::|.|.|..|:....|.|   ::.|.|:::||.::.|.:               :|..||.....
Worm     3 SILLLFSLIVLGSATEEVSRTEQTSTLFSVEGEIALPST---------------RNCAKWSAGAR 52

  Fly    72 LSINDGEFKGFVREDGQFMISGVPSGSYILDVHHPDVFYEPVRVEINPKGKFRARKVNFVQPAQI 136
            :.:|.|::.||||:|..|.:..||:|:||:.:.:.|..:||:||:|..|||.||||:..:||..:
Worm    53 IHLNHGQYMGFVRQDCTFRVDFVPTGTYIVQIENTDFVFEPIRVDITSKGKMRARKLTILQPNNV 117

  Fly   137 MQVAYPLRVKPLMPFKYFQTREQWKITDFLFSPMVLMMVLPLLLMLVLPKM-INDPETKKEIDNL 200
            ..:.||||:....|.:||:.||:|:|||.||||||||:|:||::||:|||| .||||.|||::|:
Worm   118 NTLPYPLRLSARGPARYFRKREEWRITDMLFSPMVLMLVVPLVVMLILPKMTANDPELKKEMENM 182

  Fly   201 QFPKMGNDMPEISEMLTSLLTGKQPEPKE 229
            |.||:  |||::.||:.:...|..|..|:
Worm   183 QMPKV--DMPDVGEMMANFFGGSAPAKKK 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EMC7	NP_611078.1	DUF2012	68..168	CDD:286513	42/99 (42%)
C35D10.1	NP_001033353.1	Peptidase_M14NE-CP-C_like	45..149	CDD:304370	44/103 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165395
Domainoid	1	1.000	118	1.000	Domainoid score	I3650
eggNOG	1	0.900	-	-		E1_KOG3306
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10597
Inparanoid	1	1.050	180	1.000	Inparanoid score	I2667
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51947
OrthoDB	1	1.010	-	-		D1348328at2759
OrthoFinder	1	1.000	-	-		FOG0003435
OrthoInspector	1	1.000	-	-		oto18210
orthoMCL	1	0.900	-	-		OOG6_102814
Panther	1	1.100	-	-	LDO	PTHR13605
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2915
SonicParanoid	1	1.000	-	-		X3893
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.840